Publications by authors named "Andressa C Lannes"
Curr Microbiol
September 2014
Article Synopsis
- Bacterial multiresistance is a global health concern that necessitates the development of new antimicrobials, prompting a study on N-substituted-phenylamino-5-methyl-1H-1,2,3-triazole-4-carbohydrazide derivatives.
- Four nitrofurans among the 16 tested showed strong antimicrobial activity, with minimum inhibitory and bactericidal concentrations (MIC and MBC) in the range of 1-16 μg/mL, indicating potential effectiveness against resistant strains.
- The selected derivatives displayed low cytotoxicity and theoretical risks, suggesting they could be promising alternatives to existing antimicrobials like vancomycin and ciprofloxacin for treating bacterial infections.
