Biological characterization of epimastigotes derived from trypomastigotes isolated from Brazilian chagasic patients.

Chagas disease (CD), caused by , occurs in several countries in Latin America and non-endemic countries. Heterogeneity among population has been the Achilles' heel to find a better treatment for CD. In this study, we characterized the biochemical parameters and mitochondrial bioenergetics of epimastigotes differentiated from eight  isolates (I1-I8) obtained from Brazilian CD patients.

Using a Chagas disease hospital database: a clinical and epidemiological patient profile.

Introduction: Chagas disease (CD) prevention and control rely on studies of its distribution, characteristics of individuals affected and mode of transmission. CD data in Brazil are scarce; a retrospective analysis of the clinical characteristics of 80 patients treated at the Clinical Hospital of UNICAMP, Campinas, Brazil, was performed.

Methods: Patient data records were analyzed.