Walking-related outcomes for individuals with traumatic and non-traumatic spinal cord injury inform physical therapy practice.

Objectives: To describe and compare patient demographics, inpatient lengths of stay (LOS), and walking-related functional outcomes of individuals with spinal cord injuries (SCIs) of traumatic (TSCI) and non-traumatic (NTSCI) etiologies. To contrast these features between individuals who walked from those who did not walk at discharge from inpatient rehabilitation.

Design: Prospective observational study; comparisons between TSCI and NTSCI, walkers and non-walkers.

Delta(9)-THC administered into the medial prefrontal cortex disrupts the spatial working memory.

Rationale: Delta(9)-Tetrahydrocannabinol (Delta(9)-THC) disrupts working memory. The prefrontal cortex (PFC) is involved in the processing of working memory, and its medial portion (mPFC) is part of a brain reward circuit as constituted by the mesocorticolimbic dopaminergic system.

Objective: This study examined the involvement of the mPFC in the effects of Delta(9)-THC on spatial working memory.