Publications by authors named "Andres Serradelo"
Article Synopsis
- - The study examined a prostate cancer vaccine combining Montanide ISA 51 and very small size proteoliposomes (VSSP), showing it generates a strong immune response against gonadotropin-releasing hormone (GnRH) in healthy mice.
- - When tested on DD/S mice with Shionogi carcinoma (SC) 115 cells, the vaccine led to sustained tumor growth inhibition compared to non-vaccinated controls, with some mice experiencing complete remission.
- - The research indicates that the vaccine's ability to moderately reduce testosterone levels could help delay the development of castration resistance in prostate cancer, proposing it as a potential treatment option for patients.
