Publications by authors named "Andres Paris-Munoz"
Article Synopsis
- The Helios protein, part of the Ikaros transcription family, is being studied as a potential biomarker for the progression of systemic lupus erythematosus (SLE) in both mouse models and human patients.
- Research is focusing on Helios's impact on T regulatory (Treg) cells, with changes in these cells linked to autoimmune issues.
- The review also explores the role of Helios in immune interactions and the potential for new therapies, including immunosuppressive cell transfer and using nanotechnology for targeted treatments.
T-cell-mediated autoimmunity reflects an imbalance in this compartment that is not restored by tolerogenic immune cells, e.g., regulatory T cells or tolerogenic dendritic cells (tolDCs).
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