Lin et al. (2022) discover that FGFR2 undergoes liquid-liquid phase separation with its downstream effectors SHP2 and PLCγ1, and the formation of phase separated condensates is essential for signaling competency.
View Article and Find Full Text PDFThe evolutionary stability of mutualistic interactions involving multiple partners requires "sanctioning"-the ability to influence the fitness of each partner based on its respective contribution. Sanctions must be sensitive to even small differences if even slightly less-beneficial partners could gain a fitness advantage by diverting resources away from the mutualistic service toward their own reproductive fitness. Here, we test whether legume hosts sanction even mediocre N-fixing rhizobial strains by influencing either nodule growth (which limits rhizobial cell numbers) or carbon accumulation (polyhydroxybutryate or PHB) per rhizobial cell.
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