[Immunotyping of lymphocytes in the gastric mucosa of patients infected by H. pylori in two regions with contrast in the risk of developing gastric cancer].

Unlabelled: Helicobacter pylori (H. pylori) infection involves multiple factors internal and external to the host. Among the internal factors, the immune response plays a fundamental role in the process of antigen presentation, lymphocytic response and cytokine-mediated regulatory response that are directly as sociated with disease progression and prognosis.

[Immune response Th1/Th2 to Helicobacter pylori and Helminths in co-infected patients].

Introduction: Inflammation associated with Helicobacter pylori (H. pylori) infection is linked to the development of a gastric precancerous lesion. Helminth infections could influence the pro-inflam matory response to such infection from LTCD4+ Th1 to a less harmful LTCD4+ Th2 response.

Punctual mutations in gene of clarithromycin-resistant in Colombian populations.

Aim: To characterize punctual mutations in gene of clarithromycin-resistant () and determine their association with therapeutic failure.

Methods: PCR products of gene V domain of 74 isolates; 34 resistant to clarithromycin (29 from a low-risk gastric cancer (GC) population: Tumaco-Colombia, and 5 from a high-risk population: Tuquerres-Colombia) and 40 from a susceptible population (28 from Tumaco and 12 from Túquerres) were sequenced using capillary electrophoresis. The concordance between mutations of V domain gene of and therapeutic failure was determined using the coefficient and McNemar's test was performed to determine the relationship between mutations and clarithromycin resistance.

Effect of treatment failure on the CagA EPIYA motif in strains from Colombian subjects.

Aim: To evaluate effect of treatment failure on and genotypes in () isolates from Colombia.

Methods: One hundred and seventy-six participants infected with from Colombia were treated during 14 d with the triple-standard therapy. Six weeks later, eradication was evaluated by C-Urea breath test.

Genomic variability of isolates of gastric regions from two Colombian populations.

Aim: To compare the genomic variability and the multiple colonization of () in patients with chronic gastritis from two Colombian populations with contrast in the risk of developing gastric cancer (GC): Túquerres-Nariño (High risk) and Tumaco-Nariño (Low risk).

Methods: Four hundred and nine patients from both genders with dyspeptic symptoms were studied. Seventy-two patients were included in whom was isolated from three anatomic regions of the gastric mucosa, (31/206) of the high risk population of GC (Túquerres) and (41/203) of the low risk population of GC (Tumaco).