Publications by authors named "Andres Gudino"

Background: Underlying intracranial stenosis is the most common cause of failed mechanical thrombectomy in acute ischemic stroke patients with large vessel occlusion. Adjunct emergent stenting is sometimes performed to improve or maintain reperfusion, despite limited data regarding its safety or efficacy.

Methods: We conducted a prospective multicenter observational international cohort study.

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Background: The volume of hemorrhage is a crucial factor in predicting outcomes following aneurysmal subarachnoid hemorrhage (aSAH). Although grading scales such as the Fisher score are widely used, they can lead to inaccuracies in quantifying the total blood volume because of their reliance on visual assessment. We analyzed a large cohort of patients with aSAH with a semiautomated software for the precise quantification of hemorrhage volume.

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Background And Purpose: The determination of Aneurysm wall enhancement (AWE) by human readers on visual inspection alone is subjective and prone to error. A three-dimensional (3D) method for quantifying the aneurysm wall's signal intensity (SI) enables objective determination of AWE. Inter-reader agreement and agreement between subjective and objective determination of AWE were assessed in this study.

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Article Synopsis
  • Blebs, which significantly increase the risk of intracranial aneurysm rupture, were analyzed using radiomic features to understand their unique imaging profile and mechanical interactions.
  • A detailed study involved high-resolution MRI to capture 3D models of bleb-containing aneurysms, allowing for the extraction and comparison of radiomic features between aneurysms with and without blebs.
  • The findings revealed that blebs have distinct radiomic characteristics and that certain features correlate with mechanical metrics, indicating that this analysis could improve rupture risk assessment for aneurysms.
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Article Synopsis
  • Morbidity rates for subarachnoid hemorrhage (SAH) remain high despite improvements in treatment, making it essential to use standardized outcome scales in research to evaluate new therapies effectively.
  • This review discusses various clinical outcome scales and emphasizes the need to employ standardized terminology and diagnostic criteria to accurately report outcomes related to SAH.
  • Recommendations include using established severity scales in clinical trials, conducting neuropsychological evaluations to assess cognitive function, and integrating psychological and quality-of-life assessments to fully account for the impacts of SAH on patient well-being.
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Aneurysm wall enhancement (AWE) has the potential to be used as an imaging biomarker for the risk stratification of intracranial aneurysms (IAs). Radiomics provides a refined approach to quantify and further characterize AWE's textural features. This study examines the performance of AWE quantification combined with clinical information in detecting symptomatic IAs.

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Background: Stent development has focused recently on low-profile, self-expandable stents compatible with 0.0165 inch microcatheters. The LVIS EVO is the second-generation version of the Low-Profile Visualized Intraluminal Support (LVIS) with improved visibility and resheathability.

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Emerging evidence indicates that aneurysmal subarachnoid hemorrhage (aSAH) elicits a response from both innate and adaptive immune systems. An upregulation of CD8 + CD161 + cells has been observed in the cerebrospinal fluid (CSF) after aSAH, yet the precise role of these cells in the context of aSAH is unkown. CSF samples from patients with aSAH and non-aneurysmal SAH (naSAH) were analyzed.

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Background: Aneurysm wall enhancement (AWE) has the potential to be used as an imaging biomarker for the risk stratification of intracranial aneurysms (IAs). Radiomics provides a refined approach to quantify and further characterize AWE's textural features. This study examines the performance of AWE quantification combined with clinical information in detecting symptomatic IAs.

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