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Publications by authors named "Andres G Grandea"

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Synopsis of recent research by authors named "Andres G Grandea"

  • - Andres G Grandea's research primarily focuses on understanding the mechanisms of antibody-mediated immune responses, particularly in the context of HIV and SIV, utilizing rhesus macaque models.
  • - Studies indicate that while antibody-dependent cellular cytotoxicity (ADCC) can eliminate SIV-infected cells, it may not suffice for complete protection against SIV infections, as shown by the response to the V2-specific antibody PGT145.
  • - Grandea's work also explores species-specific variations in Fcγ receptor interactions and their implications for antibody function, underscoring the challenges in translating findings from human studies to nonhuman primates due to differences in IgG subclasses and receptor affinities.

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