Publications by authors named "Andres Castaneda"
We present the clinical case of a 39-year-old woman with a medical history of juvenile idiopathic arthritis and uveitis, evaluated for abdominal pain and distension, difficulty gaining weight, and diarrhea. Blood tests were requested, including antibodies which were negative and common genetic markers, showing positivity for HLA DQ 7.5.
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- The study focuses on neurodegenerative diseases, specifically tauopathies like Pick's disease and Alzheimer's, investigating their regulatory mechanisms through epigenomic variations.
- Researchers identified key regulatory changes associated with disease progression, revealing potential new therapeutic targets and linking specific non-coding regions and transcription factor binding to target genes.
- They validated findings using CRISPR techniques and created an interactive database to visualize transcription factor occupancy and regulatory networks in single cells.
Objective: To document trends in inequity in homicide rates in Mexico for the period 2000-2021, at the state and national levels.
Methods: An observational, longitudinal ecological study was conducted in which standardized homicide mortality rates were estimated, by municipality and sex. Municipalities were classified in five groups, according to the Social Lag Index.