Publications by authors named "Andres Bustos"
Article Synopsis
- A 79-year-old woman experienced a periprosthetic fracture 8 years after knee replacement surgery, leading to the discovery of implant loosening and severe bone loss.
- She was diagnosed with a rare high-grade osteosarcoma near the prosthesis, resulting in a supracondylar femoral amputation.
- Following the procedure, the patient remained complication-free for 2 years, underscoring the need for specialized care in similar complex cases involving malignant tumors around knee implants.
Background: The metabolic reprogramming of mesenchymal stem/stromal cells (MSC) favoring glycolysis has recently emerged as a new approach to improve their immunotherapeutic abilities. This strategy is associated with greater lactate release, and interestingly, recent studies have proposed lactate as a functional suppressive molecule, changing the old paradigm of lactate as a waste product. Therefore, we evaluated the role of lactate as an alternative mediator of MSC immunosuppressive properties and its contribution to the enhanced immunoregulatory activity of glycolytic MSCs.
View Article and Find Full Text PDF[Differences in Subjective Experience Between Unipolar and Bipolar Depression].
Rev Colomb Psiquiatr
April 2017
Introduction: It is important to make distinction between bipolar and unipolar depression because treatment and prognosis are different. Since the diagnosis of the two conditions is purely clinical, find symptomatic differences is useful.
Objectives: Find differences in subjective experience (first person) between unipolar and bipolar depression.