Publications by authors named "Andrei Savu"

Background: Pyoderma gangrenosum, acne, and suppurative hidradenitis (PASH) syndrome is a rare condition characterized by clinical features of all three dermatologic conditions. The management of PASH syndrome is difficult, with no consensus on treatment guidelines. Since PASH syndrome can increase morbidity and adversely impact quality of life, better characterization of effective therapies is needed.

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Article Synopsis
  • Cutaneous immune-related adverse events (cirAEs) are common issues faced during immune checkpoint inhibitor therapy, with inadequate treatment guidelines currently available due to reliance on limited case reports.* -
  • A registry collected data on 97 cirAEs from 13 institutions, revealing a variety of treatments, including steroids, novel therapies like tacrolimus and phototherapy, and no serious adverse events reported.* -
  • The study highlights the potential of multi-institutional data collection for evaluating and improving treatment strategies for cirAEs, paving the way for more definitive treatment recommendations in the future.*
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Unlabelled: Animal bites are common worldwide. Due to the plethora of animals, there are diverse pathogens with specific associated risks and treatment algorithms. It is crucial to understand these to develop and execute appropriate management plans.

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Biological terrestrial locomotion occurs on substrate materials with a range of rheological behaviour, which can affect limb-ground interaction, locomotor mode and performance. Surfaces like sand, a granular medium, can display solid or fluid-like behaviour in response to stress. Based on our previous experiments and models of a robot moving on granular media, we hypothesize that solidification properties of granular media allow organisms to achieve performance on sand comparable to that on hard ground.

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