Publications by authors named "Andreas Theodorakakos"

The present paper focuses on the simulation of the growth and collapse of a bubble in the vicinity of a wall. Both liquid and gas phases are assumed compressible, and their interaction is handled with the volume-of-fluid method. The main interest is to quantify the influence of the induced shear stress and pressure pulse in the vicinity of the wall for a variety of bubble sizes and bubble-wall distances.

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Introduction: The functional behavior and hemodynamic characteristics of percutaneously implanted bioprosthetic valves are not known.

Methods: We created aortic models after the simulated implantation of two of the most widely used bioprosthetic valves: the Edwards SAPIEN, and the Medtronic CoreValve. By using computational fluid dynamics analysis we sought to investigate variations in the aortic flow patterns induced by the two valve designs and their association with detrimental phenomena such as vascular remodeling, vascular wall damage and thrombosis.

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Background: The ideal bifurcation stenting technique is not established, and data on the hemodynamic characteristics at stented bifurcations are limited.

Methods And Results: We used computational fluid dynamics analysis to assess hemodynamic parameters known affect the risk of restenosis and thrombosis at coronary bifurcations after the use of various single- and double-stenting techniques. We assessed the distributions and surface integrals of the time averaged wall shear stress (TAWSS), oscillatory shear index (OSI), and relative residence time (t(r)).

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Objective: To develop and implement a method for three-dimensional (3D) reconstruction of coronary arteries from conventional monoplane angiograms.

Background: 3D reconstruction of conventional coronary angiograms is a promising imaging modality for both diagnostic and interventional purposes.

Methods: Our method combines image enhancement, automatic edge detection, an iterative method to reconstruct the centerline of the artery and reconstruction of the diameter of the vessel by taking into consideration foreshortening effects.

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