Publications by authors named "Andreas Pratama Nugraha"

Article Synopsis
  • Managing extensive palatal defects after surgery is challenging for oral and maxillofacial surgeons due to limited visibility, bleeding risks, and airway management issues.
  • This case series presents two female patients with massive pleomorphic adenomas affecting speech and comfort, diagnosed through CT scans and fine needle aspiration biopsy.
  • Successful surgeries involved wide excisions and the use of surgical obturators, leading to healing without complications and maintaining speech function, emphasizing the importance of understanding tumor characteristics and anatomy for effective treatment.
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The hallmark of osteomyelitis was progressive bone destruction and sequestrum formation. In the underlying disease, like diabetes mellitus, osteomyelitis becomes severe and exacerbates the condition. It was essential for the oral and maxillofacial surgeon to comprehend its complex medical and surgical management to achieve complete disease eradication.

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Introduction And Importance: Reconstruction of alveolar bone defects caused by radicular cysts is challenging for oral and maxillofacial surgeons.

Case Presentation: Two Indonesian females had similar complaint of swelling in the vestibule area of the right mandible. Panoramic radiography showed radiolucent lesions.

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Objective:  Freeze-dried bovine bone scaffold (FDBB) or decellularized FDBB (dc-FDBB) was developed as an ideal scaffold with osteoinductive properties. This research aims to compare the osteoinductive properties marked by the expression of runt-related transcription factor-2 (RUNX2) and Osterix (OSX) and the osteogenic capacity of these scaffolds imbued with human umbilical cord mesenchymal stem cells (hUCMSCs).

Materials And Methods:  This study was performed in five experimental groups: a negative control group (C-) of hUCMSCs with a normal growth medium, a positive control group (C + ) of hUCMSCs with an osteogenic medium, experimental group 1 (E1) with an FDBB conditioned medium (CM), and experimental group 2 (E2) with a dc-FDBB-CM, and a third experimental group (E3) consisting of a DBBM-CM.

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