Publications by Andreas Nessel

Publications by authors named "Andreas Nessel"

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PTEN-inhibition by zinc ions augments interleukin-2-mediated Akt phosphorylation.

Laura Marie Plum Anne Brieger Gabriela Engelhardt Silke Hebel Andreas Nessel

Metallomics

July 2014

Free zinc ions (Zn(2+)) participate in several signaling pathways. The aim of the present study was to investigate a potential involvement of Zn(2+) in the PI3K/Akt pathway of interleukin (IL)-2 signaling in T-cells. The IL-2 receptor triggers three major pathways, ERK1/2, JAK/STAT5, and PI3K/Akt.

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