Publications by authors named "Andreas Meister"
Background: Thermal dose in clinical hyperthermia reported as cumulative equivalent minutes (CEM) at 43 °C (CEM43) and its variants are based on direct thermal cytotoxicity assuming Arrhenius 'break' at 43 °C. An alternative method centered on the actual time-temperature plot during each hyperthermia session and its prognostic feasibility is explored.
Methods And Materials: Patients with bladder cancer treated with weekly deep hyperthermia followed by radiotherapy were evaluated.
To present the outcomes of a pilot study with hyperthermia (HT) and radiotherapy (RT) in elderly patients of muscle-invasive bladder cancers (MIBC) unfit for surgery or chemoradiotherapy (CTRT). Sixteen elderly patients with unifocal or multifocal MIBCs received a total dose of 48 Gy/16 fractions/4 weeks or 50 Gy/20 fractions/4 weeks, respectively. HT with a radiofrequency HT unit was delivered once weekly for 60 min before RT and a mean temperature of 41.
View Article and Find Full Text PDFPurpose: To assess feasibility and safety of conventionally fractionated radiotherapy (cfRT) in patients with hepatocellular carcinoma (HCC).
Methods: Patients with histologically confirmed stage cT1-4, cN0-1 HCC and Child-Pugh Score (CPS) A or B disease were included in a phase I multicenter trial. Metastatic HCC were allowed if ≥90% of total tumor volume was located within the liver.
Article Synopsis
- This study assessed the effectiveness of loco-regional hyperthermia (HT) combined with radiotherapy (RT) and/or chemotherapy (CT) for treating elderly patients with muscle-invasive bladder cancer (MIBC), focusing on outcomes such as survival and treatment side effects.
- Twenty MIBC patients received either HT with RT or HT with CT and RT, with results showing that HT combined with RT led to better local disease control, fewer severe side effects, and better overall survival rates compared to HT combined with CT and RT.
- The findings suggest that using thermal radiosensitisation increases the effectiveness of treatment by allowing for higher doses of radiation and shorter treatment times, indicating a need for further research on the