Publications by authors named "Andreas M Halder"

Arthroplasty of the hip has become one of the most successful surgical interventions and has seen significant advancements over the last century. With these developments, patient expectations have shifted from merely achieving pain-free daily mobility to anticipating a full recovery, including the ability to participate in sports. This shift has driven innovations in prosthetic materials and surgical techniques, such as the development of wear-resistant materials like highly cross-linked polyethylene and the adoption of minimally invasive procedures to enhance recovery.

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Background: Surgical techniques in two-stage revision total knee arthroplasty (rTKA) include the use of articulating spacers and static spacers. Shortening of the patellar tendon could be a reason for inferior functional outcomes in two-stage septic rTKA . The aim of this study was to determine if articulating spacers also have negative effects on the extensor mechanism in rTKA.

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Article Synopsis
  • The study aimed to identify patient-specific factors that increase the likelihood of needing a blood transfusion after total hip arthroplasty (THA), where transfusions have become rare.
  • Researchers analyzed 2,892 elective THA patients and assessed various factors like age, BMI, ASA grade, sex, and preoperative hemoglobin levels to determine their impact on transfusion risk.
  • The results indicated that being over 73 years old, having a hemoglobin level below 7.6 mmol/l, and a BMI of 35.4 kg/m² or higher were significant predictors of needing a transfusion, allowing for preventive strategies to be implemented based on these factors.
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Background: There is a scarcity of scientific data regarding the correlation between alignment techniques during total knee arthroplasty (TKA) and blood loss as well as transfusion rates. This study's hypothesis posited that intramedullary-aligned (IM) TKA exhibits higher blood loss and transfusion rates when contrasted with extramedullary-aligned (EM) TKA.

Methods: We conducted a retrospective examination of 883 patients who underwent total knee arthroplasty (TKA) in 2021 at a solitary orthopedic center in Germany.

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Aims: A substantial fraction of patients undergoing knee arthroplasty (KA) or hip arthroplasty (HA) do not achieve an improvement as high as the minimal clinically important difference (MCID), i.e. do not achieve a meaningful improvement.

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Background: Little scientific evidence exists on blood loss and transfusion rates depending on the fixation technique. The hypothesis of this study was that the blood loss and transfusion rate are lower in cemented and hybrid total hip arthroplasty (THA) compared to cementless THA.

Methods: We retrospectively compared a total of 1500 patients who received either cementless, cemented, hybrid or reverse hybrid THA.

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Purpose: Conventional instruments for total knee arthroplasty (TKA) have limited accuracy. The occurrence of outliers can negatively influence the clinical outcome and long-term survival of the implant. Orthopaedic robotic systems were developed to increase the accuracy of implant positioning and bone resections.

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Background: Over the last years, new transfusion guidelines and pharmaceuticals have been introduced in primary and revision total hip and knee arthroplasty (P-THA, P-TKA, R-THA, R-TKA). In the US, a substantial decrease in transfusions has been observed in recent years. Little data exists on the subject in Europe.

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  • The study examines the impact of time to surgery (TTS) on mortality and complications in patients with proximal femoral fractures, utilizing data from over 106,000 hospitalizations between 2015 and 2017.
  • It reveals that a longer TTS increases the risk of complications, particularly for pertrochanteric fractures when surgery is delayed beyond 2 days, with a heightened risk noted at 3 and 4-7 days as well.
  • The conclusion indicates that waiting longer for surgery correlates with higher general complication risks, influenced by the fracture type and surgical method used.
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Background: In case of isolated medial and patellofemoral joint arthritis, bicompartmental knee arthroplasty (BCA) is an alternative to total knee arthroplasty (TKA). The purpose of our prospective, randomized study is to compare the clinical outcome of BCA vs TKA.

Methods: Eighty patients with isolated medial and patellofemoral osteoarthritis were randomly assigned to either BCA or TKA.

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  • The study examines how the volume of revision total knee arthroplasties (R-TKAs) performed at hospitals affects the rates of re-revision and other complications after surgery.
  • Analyzing data from over 23,000 R-TKAs, researchers found that hospitals performing fewer than 25 R-TKAs per year had a higher risk of re-revision within a year.
  • The conclusion suggests that performing complex surgeries like R-TKAs in specialized centers with higher experience may improve patient outcomes.
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  • The study investigates the connection between the number of revision total hip arthroplasties (R-THAs) performed by hospitals and the outcomes for patients, focusing on complications and mortality rates post-surgery.
  • Analyzing data from over 17,000 R-THA procedures, the researchers found that hospitals with higher volumes (more than 25 or 53 R-THAs a year) had lower rates of complications and mortality compared to those that performed fewer surgeries.
  • The conclusion suggests that to ensure better patient outcomes, complex surgeries like R-THA should ideally be conducted in specialized hospitals with higher surgical volumes.
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Background: The aim of our study is to evaluate the association of body mass index (BMI) and the risk of postoperative complications, mortality, and revision rates following primary total hip arthroplasty given other potentially confounding patient characteristics in a large cohort study.

Methods: Using nationwide billing data for inpatient hospital treatment of the biggest German healthcare insurance, 131,576 total hip arthroplasties in 124,368 patients between January 2012 and December 2014 were included. Outcomes were 90-day mortality, 1-year revision procedures (with and without removal or exchange of implants), 90-day surgical complications, 90-day femoral fractures, and overall complications.

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Background: Reported survival rates of unicondylar knee arthroplasty (UKA) vary considerably. The influences of patient characteristics and the type of implant have already been examined. This analysis investigated the influence of hospital volume on 5-year-survival rate, using administrative claims data of Germany's largest health insurance provider.

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Introduction: Major bone defects are the greatest challenge in hip revision arthroplasty.

Methods: In a prospective, consecutive nonrandomised study we followed up 74 patients with Type III (AAOS) acetabular bone defects who underwent revision hip arthroplasty with bone grafting and implantation of a Burch-Schneider anti-protrusion cage (APC). The patients were examined pre- and postoperatively according to a standardised clinical and radiological protocol.

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  • Avascular necrosis of the knee following arthroscopic surgery has been studied, but this article focuses on the often misdiagnosed condition of osteonecrosis specifically affecting the medial tibial plateau.
  • The study involved analyzing the medical records and X-rays of six elderly Caucasian females who had isolated osteonecrosis without any trauma, with three of them having undergone previous arthroscopic surgery.
  • The exact cause of the osteonecrosis remains uncertain, but it highlights the need to consider it as a potential reason for ongoing knee pain after surgery, while the link between surgical treatment and the development of necrosis should be approached cautiously.
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Study Design: Within-subject, repeated-measures design.

Objectives: To measure tibiofemoral contact forces during cycling in vivo and to quantify the influences of power, pedaling cadence, and seat height on tibiofemoral contact forces.

Background: Cycling is usually classified as a low-demand activity for the knee joint and is therefore recommended for persons with osteoarthritis and rehabilitation programs following knee surgery.

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The clinical and radiological results of Vancouver type B2 and B3 peri-prosthetic fractures treated with an uncemented Wagner revision stem (3rd generation) were analysed. Two groups were identified, 15 patients had a B2 and 14 cases a B3 periprosthetic fracture. The mean follow-up was 74 months after the index operation.

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Knee osteoarthritis occurs predominately at the medial compartment. To unload the affected compartment, valgus braces are used which induce an additional valgus moment in order to shift the load more laterally. Until now the biomechanical effect of braces was mainly evaluated by measuring changes in external knee adduction moments.

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Background: Detailed information about the loading of the knee joint is required for various investigations in total knee replacement. Up to now, gait analysis plus analytical musculo-skeletal models were used to calculate the forces and moments acting in the knee joint. Currently, all experimental and numerical pre-clinical tests rely on these indirect measurements which have limitations.

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Background: This multicenter, multiple-dose, randomized, double-blind, parallel-group study compared the analgesic efficacy and safety of two dosing regimens of parecoxib sodium (parecoxib) versus placebo after total hip arthroplasty.

Methods: On study Day 1, 490 patients received a postoperative initial loading dose of IV parecoxib 40 mg, followed by a re-dose of parecoxib 20 mg in 484 of 490 patients. Subsequently, 479 randomized patients received double-blind treatment with parecoxib 20 mg bid (n = 159), parecoxib 20 mg qd (n = 159) followed by placebo, or placebo (n = 161) on Day 2.

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