Electrochemical treatment: An investigation of dose-response relationships using an isolated liver perfusion model.

Background/aim: Ablative techniques such as radiofrequency ablation or non-thermal electrochemical treatment (ECT) are used to manage unresectable liver metastases. Although ECT is not affected by the cooling effect from adjacent vessels, there is a paucity of data available on ECT.

Materials And Methods: We used porcine livers to establish an organ model with portal venous and hepatic arterial blood flow for a standardized analysis of the relationship between dose (electric charge) and response (volume of necrosis).

Intrahepatic radiofrequency ablation versus electrochemical treatment ex vivo.

Background: Radiofrequency ablation (RFA) and electrochemical treatment (ECT) are two methods of local liver tumor ablation. A reproducible perfusion model allowed us to compare these methods when applied in proximity to vascular structures.

Material And Methods: In a porcine liver perfusion model, we used RFA (group A) and ECT (group B) to perform ablations under ultrasound guidance within 10 mm of a vessel and examined the induced necrosis macroscopically and histologically.

CT-guided radiofrequency ablation in patients with hepatic metastases from breast cancer.

The purpose of this study was to evaluate technical success, technique effectiveness, and survival following radiofrequency ablation for breast cancer liver metastases and to determine prognostic factors. Forty-three patients with 111 breast cancer liver metastases underwent CT-guided percutaneous radiofrequency (RF) ablation. Technical success and technique effectiveness was evaluated by performing serial CT scans.

Magnetic resonance imaging and correlative gross anatomy of the ligamentum semicirculare humeri (rotator cable).

The purpose of this study has been to demonstrate macroscopic and MRI anatomy of the so-called rotator cable, otherwise known as the ligamentum semicirculare humeri (LSCH) of the superior shoulder joint capsule. Twelve shoulder joints from eight cadavers were dissected; seven of which, from four of the cadavers, were studied using MR arthrography (1.5-Tesla device Somatom Symphony, Siemens, Erlangen, Germany) prior to dissection.

Radiofrequency ablation (RFA): development of a flow model for bovine livers for extensive bench testing.

Purpose: To develop a flow model for bovine livers for extensive bench testing of technical improvements or procedure-related developments of radiofrequency ablation excluding animal experiments.

Methods: The perfusion of bovine livers directly from the slaughterhouse was simulated in a liver perfusion tank developed for the experimental work. The liver perfusion medium used was a Tyrode solution prepared in accordance with physiologic criteria (as for liver transplants) which was oxygenated by an oxygenator and heated to 36.

Effects of vascular perfusion on coagulation size in radiofrequency ablation of ex vivo perfused bovine livers.

Objectives: A standardized perfused ex vivo bovine liver model was used to evaluate the effect of organ perfusion on coagulation size and energy deposition during radiofrequency ablation (RFA) procedures.

Materials And Methods: Bovine livers were perfused in a tank after rinsing the prepared liver vessels with anticoagulants. Tyrode's solution, oxygenated and heated to 36.

Hepatocellular carcinoma: interventional bridging to liver transplantation.

Hepatocellular carcinoma (HCC) is one of the most common solid cancers worldwide with surgery being considered the treatment of choice. However, it is limited in view of the hepatic dysfunction and high recurrence rates associated with the disease. Liver transplantation offers the advantage of both, eradicating the tumor and treating the underlying liver disease and is the only chance for cure in patients suffering from HCC.

Radiofrequency thermal ablation: increase in lesion diameter with continuous acetic acid infusion.

Purpose: To evaluate the influence of continuous infusion of acetic acid 50% during radiofrequency ablation (RFA) on the size of the thermal lesion produced.

Methods: Radiofrequency (RF) was applied to excised bovine liver by using an expandable needle electrode with 10 retractable tines (LeVeen Needle Electrode, RadioTherapeutics, Sunnyvale, CA) connected to a commercially available RF generator (RF 2000, RadioTherapeutics, Sunnyvale, CA). Experiments were performed using three different treatment modalities: RF only (n = 15), RF with continuous saline 0.

Radiofrequency ablation in metastatic disease.

The liver is the most common site of metastas from colorectal cancer. Hepatic metastases are the major cause of morbidity and mortality in those patients. Surgical resection provides the greatest potential for cure in patients with secondary liver tumors but can be offered to only a small number of patients (5%-20%).

Experimental functional analysis of self-expanding stents using a new developed ex vivo model.

Objective: To modify an ex vivo test procedure for balloon expandable stents as a means to evaluate the mechanical properties of self-expanding stents.

Methods: Ten stents each of 7 different stent models measuring 10 mm in diameter (LUMINEXX Vascular Stent/Memotherm-FLEXX Vascular Stent [identical to Bard], Jostent SelfX, Jostent SelfX high radial force [Jomed], sinus-Repo stent, sinus-SuperFlex stent [Optimed], S.M.

Resistance to hoop stress in balloon expandable stents: evaluation in an ex vivo model.

Rationale And Objectives: To develop a new model for a more realistic evaluation of radial strength and elastic recoil of balloon expandable stents using a new ex vivo model in human cadaver bifurcations of the aorta.

Materials And Methods: Four different stents (each group n = 10) were implanted in cadaver common iliac arteries. Randomization was performed either to right or left iliac artery.

Retained surgical sponge with migration into the duodenum and persistent duodenal fistula.

Migration of a retained surgical sponge into the bowel is a rare cause of bowel obstruction. Thus far, there have not been any reports that the site of initial migration of the sponge was identified by imaging studies or surgical exploration because the onset of symptoms is usually delayed. Unique about the case presented herein is that a barium meal follow-through study revealed a duodenal fistula that had developed after uneventful cholecystectomy due to a retained surgical sponge that had migrated into the duodenum and obstructed the distal jejunum.