Publications by authors named "Andreas Killinger"

Article Synopsis
  • Hydroxyapatite (HAp) coatings are used on bone implants to enhance biocompatibility and promote bone growth, but they can still lead to infections.
  • This study explored the use of high-velocity suspension flame spraying (HVSFS) to create thin HAp coatings and tested the effects of varying gas parameters and copper (Cu) additions on their properties and effectiveness.
  • Results indicated that using medium gas parameters and adding 1 wt.% Cu provided a good balance between antibacterial properties and biocompatibility, effectively reducing bacterial counts while limiting cytotoxic effects.
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Article Synopsis
  • Prosthesis loosening is a common implant failure caused by insufficient bonding between the implant and surrounding bone, often compounded by bacterial infection and biofilm.
  • Using bioconductive and biodegradable calcium phosphate (CaP) coatings with incorporated antibacterial agents can enhance both bone integration and combat bacterial growth.
  • This study focuses on creating Cu-doped CaP coatings with better porosity and antibacterial properties, showing good biocompatibility and effective antimicrobial action against various bacterial strains.
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High-velocity oxygen fuel (HVOF) spraying is a promising technique for depositing protective coatings. The performances of HVOF-sprayed coatings are affected by in-flight particle properties, such as temperature and velocity, that are controlled by the spraying parameters. However, obtaining the desired coatings through experimental methods alone is challenging, owing to the complex physical and chemical processes involved in the HVOF approach.

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In the present work, we test four thin coatings for titanium implants, namely, bioglass, GB14, Beta-Tricalciumphosphate (β-TCP) and hydroxyapatite (HA) with and without incorporated copper ions for their osteointegrative capacity. A rabbit drill hole model for time intervals up to 24 weeks was used in this study. Implant fixation was evaluated by measuring shear strength of the implant/bone interface.

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Bone defects introduced by accidents or diseases are very painful for the patient and their treatment leads to high expenses for the healthcare systems. When a bone defect reaches a critical size, the body is not able to restore this defect by itself. In this case a bone graft is required, either an autologous one taken from the patient or an artificial one made of a bioceramic material such as calcium phosphate.

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Thermal spraying of metal materials is one of the key applications of this technology in industry for over a hundred years. The variety of metal-based feedstocks (powders and wires) used for thermal spray is incredibly large and utilization covers abrasion and corrosion protection, as well as tribological and electrical applications. Spraying metals using suspension- or precursor-based thermal spray methods is a relatively new and unusual approach.

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One of the most common causes of implant failure is aseptic prosthesis loosening. Another frequent complication after prosthesis implant is the microbial colonization of the prosthesis surface, which often leads to a replacement of the prosthesis. One approach to reduce these complications is the application of bioactive substances to implant surfaces.

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Objectives: Wettability is increasingly considered to be an important factor determining biological responses to implant materials. In this context, the purpose of this study was to compare the dynamic wettability of dental implants made from different bulk materials and modified by different surface modifications, and to analyze the respective changes of wettability upon irradiating these implants by UV-A or UV-C light.

Methods: Four original screw-type implants were investigated: One grit-blasted/acid-etched and one anodically oxidized titanium, one zirconia and one polyetheretherketone implant.

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In cementless fixation of metallic prostheses, bony ingrowth onto the implant surface is often promoted by osteoconductive plasma-sprayed hydroxyapatite coatings. The present work explores the use of the innovative High Velocity Suspension Flame Spraying (HVSFS) process to coat Ti substrates with thin homogeneous hydroxyapatite coatings. The HVSFS hydroxyapatite coatings studied were dense, 27-37μm thick, with some transverse microcracks.

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