This 14-year cohort study investigated the long-term safety of ustekinumab, a biologic treatment for psoriasis, using data from Danish national registers.
The study compared safety outcomes like cancers and serious infections in ustekinumab users against patients receiving other systemic treatments, including non-biologics and various biologic therapies.
Results showed that ustekinumab is generally safe, with no major safety concerns identified, and users were younger and had different gender distributions compared to users of other treatments.
Cesarean delivery rates in Dar es Salaam have risen from 17% in 2015 to 26% in 2022 without corresponding improvements in perinatal outcomes, indicating potential overuse and highlighting the need to manage prolonged labor effectively.
This study aimed to determine what percentage of cesarean deliveries indicated as due to prolonged labor occurred in women with otherwise uncomplicated labor progression.
Findings showed that out of 1517 first-time cesarean deliveries, nearly half (47.9%) had prolonged labor as the written indication, but 53.3% of these cases occurred despite the labor progressing normally, raising concerns about unnecessary cesarean deliveries.
Assessing measles risk in infants 6-12 months is crucial, but there's limited data on ELISA tests for those under 9 months.
A study used a commercial ELISA kit to evaluate measles immunity in infants aged 5-7 months, comparing results with the more complex PRNT method at various time points after vaccination.
Findings showed low correlation between ELISA and PRNT results, with ELISA often underestimating immunity, indicating a need for more accurate testing to prevent vaccine failures during outbreaks.*