Non-invasive estimation of relative pressure for intracardiac flows using virtual work-energy.

Intracardiac blood flow is driven by differences in relative pressure, and assessing these is critical in understanding cardiac disease. Non-invasive image-based methods exist to assess relative pressure, however, the complex flow and dynamically moving fluid domain of the intracardiac space limits assessment. Recently, we proposed a method, νWERP, utilizing an auxiliary virtual field to probe relative pressure through complex, and previously inaccessible flow domains.

A class of analytic solutions for verification and convergence analysis of linear and nonlinear fluid-structure interaction algorithms.

Fluid-structure interaction (FSI) problems are pervasive in the computational engineering community. The need to address challenging FSI problems has led to the development of a broad range of numerical methods addressing a variety of applicationspecific demands. While a range of numerical and experimental benchmarks are present in the literature, few solutions are available that enable both verification and spatiotemporal convergence analysis.

Enabling Detailed, Biophysics-Based Skeletal Muscle Models on HPC Systems.

Realistic simulations of detailed, biophysics-based, multi-scale models often require very high resolution and, thus, large-scale compute facilities. Existing simulation environments, especially for biomedical applications, are typically designed to allow for high flexibility and generality in model development. Flexibility and model development, however, are often a limiting factor for large-scale simulations.

Validation of a non-conforming monolithic fluid-structure interaction method using phase-contrast MRI.

This paper details the validation of a non-conforming arbitrary Lagrangian-Eulerian fluid-structure interaction technique using a recently developed experimental 3D fluid-structure interaction benchmark problem. Numerical experiments for steady and transient test cases of the benchmark were conducted employing an inf-sup stable and a general Galerkin scheme. The performance of both schemes is assessed.