Publications by authors named "Andreas Harmsen"
Mol Neurodegener
January 2010
Article Synopsis
- Alzheimer's disease (AD) shows a distinct pattern of amyloid beta (Abeta) isoforms in cerebrospinal fluid (CSF), varying between sporadic AD (SAD) and familial AD (FAD), which may indicate different underlying mechanisms of the disease.
- In a study with 48 participants, significant differences in the levels of various Abeta isoforms were found, particularly low CSF levels of Abeta1-42 and high levels of Abeta1-16 in SAD and FAD patients compared to healthy controls.
- The findings suggest that specific Abeta isoform patterns, especially the low levels of Abeta1-37, Abeta1-38, and Abeta1-39 in F
