Publications by authors named "Andreas Graw"
Article Synopsis
- Myosin motors are crucial for various cellular functions in eukaryotic cells, such as generating force and transporting materials, but how they precisely regulate speed and efficiency has been largely unclear.*
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- This study identifies a specific phosphorylation event on class VI myosin (MYO6) that significantly boosts its motor speed by enhancing ATPase activity, with the kinase DYRK2 being responsible for this modification.*
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- The research utilizes several techniques, including single-molecule studies and molecular dynamics simulations, revealing that phosphorylation alters MYO6's function, making it a more effective and stronger motor by modifying its interaction networks.*
