Publications by authors named "Andreas E Welch"
Article Synopsis
- Cross-disciplinary approaches from physics and mechanics are enhancing our understanding of morphogenesis in embryonic development, but measuring mechanical properties remains challenging, especially in epithelial tissues.
- A novel technique developed for the chick embryo allows for the quantitative application of external forces (1-100 N) to the endodermal epithelium, revealing unexpected mechanical behaviors such as cell heterogeneity and strong mechanical interactions between different tissue types.
- This method demonstrates that moderate forces (around 10 N) can significantly impact embryonic structures, like unzipping the neural tube during neurulation, thereby providing new insights into the mechanics of morphogenesis in early development.
