Publications by authors named "Andreas Douros"
Article Synopsis
- Wound healing is a major focus in healthcare, especially for vulnerable populations; this study explores the healing effects of resin and bark extracts from a plant native to Cyprus in a mouse model.
- Researchers used male SKH-hr2 mice with induced wounds to test hydrogel formulations containing varying concentrations of these plant extracts and assessed their efficacy through several methods, including clinical observations and advanced imaging techniques.
- The findings suggest that the 10% resin formulation was the most effective, with chemical analysis revealing compounds like abietic acid that could explain the positive results, highlighting the need for further study on herbal treatments in wound care.
The phytochemical analysis of the polar extracts of needles yielded 20 compounds, namely from the methanol extract we isolated three flavonoids (-), one hydrolysable tannin (), eleven phenolic derivatives (-) and one apocarotenoid (), while from the methanol: water (5:1) extract we isolated four flavonoids (-). Chemical structures of all isolated compounds were determined by 1D, 2D-NMR (1 Dimension, 2 Dimensions Nuclear Magnetic Resonance) and UV-Vis (Ultraviolet-Visible) spectroscopy. Furthermore, the antioxidant potentials and the anti-inflammatory activities of both crude extracts and isolates were evaluated through DPPH radical scavenging capability, linoleic acid lipid peroxidation inhibition, and soybean LOX inhibition assays.
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