Immunomodulatory and Inhibitory Effect of Immulina, and Immunloges in the Ig-E Mediated Activation of RBL-2H3 Cells. A New Role in Allergic Inflammatory Responses.

Immulina, a high-molecular-weight polysaccharide extract from the cyanobacterium () is a potent activator of innate immune cells. On the other hand, it is well documented that exerts anti-inflammatory effects and showed promising effects with respect to the relief of allergic rhinitis symptoms. Taking into account these findings, we decided to elucidate whether Immulina, and immunLoges (a commercial available multicomponent nutraceutical with Immulina as a main ingredient) beyond immune-enhancing effects, might also exert inhibitory effects in the induced allergic inflammatory response and on histamine release from RBL-2H3 mast cells.

Ethanol in herbal medicinal products for children : Data from pediatric studies and pharmacovigilance programs.

Herbal medicinal products are indispensable in children, e. g., in functional gastrointestinal diseases and coughs and colds, especially when available in liquid dosing forms for which dosing can be adapted ideally to different age groups.

Intravenous vitamin C in the treatment of shingles: results of a multicenter prospective cohort study.

Background: Vitamin C is an immune-relevant micronutrient, which is depleted in viral infections and this deficiency seems to play a critical role in the pathogenesis of herpes infections and in the development of postherpetic neuralgia. The objective of this observational multicenter study was to evaluate the utilization, safety and efficacy of intravenously administrated vitamin C in patients with shingles.

Material/methods: Between April 2009 and December 2010 16 general practitioners recorded data of 67 participants with symptomatic herpes zoster who received vitamin C intravenously (Pascorbin® 7.

[Time and again it hits the little ones: herbal therapy for childhood diarrhea].

Acute diarrhea is amongst the most common childhood illnesses. Of paramount importance is an oral rehydration with glucose-electrolyte solutions. A number of herbal therapies are available to shorten the duration of the diarrhea and to alleviate the unpleasant symptoms.

Extract of Lycopus europaeus L. reduces cardiac signs of hyperthyroidism in rats.

Extracts from the plant Lycopus europaeus L. are traditionally used in mild forms of hyperthyroidism. High doses caused a reduction of TSH or thyroid hormone levels in animal experiments, whereas in hyperthyroid patients treated with low doses of Lycopus an improvement of cardiac symptoms was reported without major changes in TSH or thyroid hormone concentrations.

Dianionic complexes with hexacoordinate silicon(IV) or germanium(IV) and three bidentate ligands of the hydroximato(2-) type: syntheses and structural characterization in the solid state.

Reaction of Si(OMe)(4) with acetohydroxamic acid or benzohydroxamic acid and HNMe(2) (molar ratio 1:3:2) in MeCN yielded dimethylammonium fac-tris[acetohydroximato(2-)]silicate (fac-5) and N,N-dimethylacetamidinium fac-tris[benzohydroximato(2-)]silicate (fac-8), respectively. Reaction of Si(OMe)(4) with benzohydroxamic acid and HNMe(2) (molar ratio 1:3:2) or ethane-1,2-diamine (molar ratio 1:3:1) in MeOH gave dimethylammonium fac-tris[benzohydroximato(2-)]silicate-methanol (fac-6.MeOH) and ethane-1,2-diammonium mer-tris[benzohydroximato(2-)]silicate-dimethanol (mer-9.