Publications by authors named "Andreas A Schuppert"
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Synopsis of recent research by authors named "Andreas A Schuppert"
- Andreas A Schuppert's research primarily investigates the biological basis of diseases and cellular behaviors using advanced stem cell technologies and genetic engineering, exemplified by his work on Lesch-Nyhan disease, which highlighted impaired energy metabolism in dopaminergic cells due to HPRT1 mutations.
- He conducted a systematic study on the proteostasis network and its deregulation in cancer, revealing the critical importance of proteome balance for cellular health and establishing connections between proteostasis imbalances and various human diseases.
- Schuppert's exploration of murine embryonic stem cell heterogeneity focused on the dynamic expression of Nanog and its role in maintaining stem cell identity, providing insights into the regulatory mechanisms that govern stem cell behavior at the single-cell level.