Publications by authors named "Andrea Zancanaro"
Plasma phosphorylated-tau217 (p-tau217) has been shown to be one of the most accurate diagnostic markers for Alzheimer's disease. No studies have compared the clinical performance of p-tau217 as assessed by the fully automated Lumipulse and single molecule array (SIMOA) AlZpath p-tau217. The study included 392 participants, 162 with Alzheimer's disease, 70 with other neurodegenerative diseases with CSF biomarkers and 160 healthy controls.
View Article and Find Full Text PDFBackground: The Boston Cognitive Assessment (BOCA) is a self-administered online test developed for cognitive screening and longitudinal monitoring of brain health in an aging population. The study aimed to validate BOCA in an Italian population and to investigate the convergent validity with the Montreal Cognitive Assessment (MOCA) in healthy ageing population and patients within the Alzheimer Disease spectrum.
Methods: BOCA was administered to 150 participants, including cognitively healthy controls (HC, n = 50), patients with mild cognitive impairment (MCI, n = 50), and dementia (DEM, n = 50).
Background: Plasma phosphorylated-tau217 (p-tau217) has been shown to be one of the most accurate diagnostic markers for Alzheimer's disease (AD). No studies have compared the clinical performance of p-tau217 as assessed by the fully automated Lumipulse and SIMOA ALZpath p-tau217.
Aim: To evaluate the diagnostic accuracy of Lumipulse and SIMOA plasma p-tau217 assays for AD.
Article Synopsis
- - Systemic capillary leak syndrome (SCLS) is a rare condition characterized by episodes of low blood pressure, low albumin levels, and increased concentration of blood components caused by fluid leakage from blood vessels, which can be life-threatening.
- - A 49-year-old man with no prior health issues experienced a severe episode following flu-like symptoms, resulting in critical health complications and high levels of various lab markers, leading to a diagnosis of SCLS after initial treatments with steroids and plasma expanders.
- - Despite treatment, the patient suffered a new crisis and ultimately died from severe complications, highlighting the unpredictable nature of SCLS and the need for better management strategies for acute episodes due to limited research on the condition.
We describe the case of 79-year-old man admitted to our general hospital for a 6-week history of progressive dysphagia to solids and liquids associated with weight loss. To reach a diagnosis a total body CT scan with low-osmolality iodinate contrast agent was performed. Two hours later the patient developed an acute respiratory failure requiring orotracheal intubation and mechanical ventilation.
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