Time-correlated single photon Raman spectroscopy at megahertz repetition rates.

Significant improvements in time-correlated single photon counting (TCSPC) Raman spectroscopy acquisition times can be achieved through exploitation of megahertz (MHz) laser repetition rates. We have developed a TCSPC Raman spectroscopy system based on a high peak power (>40) pulsed laser, a high pulse repetition rate (40 MHz), a custom /1.5 spectrometer, and a 512 spectral channel × 16 time bin single photon avalanche diode line sensor.

Prenatal exposure to a cannabinoid receptor agonist does not affect sensorimotor gating in rats.

Clinical evidence suggests that prenatal exposure to cannabis may be conducive to long-term neurobehavioral impairments in executive and attentional domains. Such sensorimotor alterations might be related to disorders in gating functions. Hence, the present study was undertaken to assess the effects of long-term prenatal exposure to WIN 55,212-2, a potent cannabinoid receptor agonist, on prepulse inhibition of the acoustic startle reflex, a well-validated paradigm to test sensorimotor gating.