Publications by authors named "Andrea Tooley"

Purpose: Online health information seekers may access information produced by artificial intelligence language models such as ChatGPT (OpenAI). The medical field may pose a significant challenge for incorporating these applications given the training and experience needed to master clinical reasoning. The objective was to evaluate the performance of ChatGPT responses compared to human oculofacial plastic surgeon (OPS) responses to FAQs about an upper eyelid blepharoplasty procedure.

View Article and Find Full Text PDF

Purpose: To describe the outcomes of hyperbaric oxygen therapy (HBOT) for patients with central retinal artery occlusion (CRAO) at a single tertiary care center.

Design: Retrospective clinical cohort study.

Methods: Medical records of all patients diagnosed with CRAO who received HBOT at Mayo Clinic in Rochester, Minnesota from January 1, 2009 to December 31, 2020 were reviewed to confirm diagnosis, time from onset to presentation, exam findings, treatments, and follow-up data.

View Article and Find Full Text PDF
Article Synopsis
  • The study analyzed the occurrence and features of ocular adnexal tumors in Olmsted County, Minnesota, over a decade from 2006 to 2015.
  • During this period, 717 patients were diagnosed with ocular adnexal tumors, predominantly benign eyelid lesions, with an incidence rate of 59.7 per 100,000 individuals per year.
  • The findings highlighted that while most tumors were benign, a significant number of malignant cases were also identified, particularly basal and squamous cell carcinomas, underscoring the need for awareness in clinical practice for diagnosis and referrals.
View Article and Find Full Text PDF

Sino-orbital cutaneous fistulas (SOCFs) are a rare and challenging complication from conditions including granulomatosis with polyangiitis. SOCFs are difficult to manage due to poor vascular supply, compromised tissue, and systemic immunocompromise, which lead to a high rate of recurrence. Given the overall rarity of SOCFs, optimal surgical repair remains controversial, with options ranging from conservative management, onlay grafts, and vascularized flaps.

View Article and Find Full Text PDF

Background: Following its Food and Drug Administration approval in January 2020, we examined the impact of teprotumumab on thyroid eye disease (TED) clinical practices.

Methods: Across 3 referral centers from January 1, 2018, to December 30, 2022, we retrospectively analyzed demographics, clinical features, treatment choices, and insurance status of patients with active, moderate to severe TED.

Results: Of 74 patients recommended for medical therapy, 53% received collaborative recommendations from endocrinologists and ophthalmologists in a TED clinic.

View Article and Find Full Text PDF

Purpose: Mohs micrographic surgery with immunohistochemistry allows for same-day comprehensive margin assessment of melanoma in situ prior to subspecialty reconstruction. This study describes the oncologic and reconstructive outcomes of eyelid and periorbital melanoma in situ and identifies risk factors for complex reconstructive demands.

Methods: Retrospective case series of all patients treated with Mohs micrographic surgery with immunohistochemistry for melanoma in situ affecting the eyelids or periorbital region from 2008 to 2018 at a single institution.

View Article and Find Full Text PDF

Objective: To determine the appropriateness of ophthalmology recommendations from an online chat-based artificial intelligence model to ophthalmology questions.

Patients And Methods: Cross-sectional qualitative study from April 1, 2023, to April 30, 2023. A total of 192 questions were generated spanning all ophthalmic subspecialties.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates whether specific components of ophthalmology residency applications can predict future performance of residents across multiple domains.
  • It involves a review of residency application materials and performance evaluations of graduates from 2006 to 2018 at seven U.S. ophthalmology residency programs.
  • Key findings indicate that higher USMLE Step 1 scores, honors in core clerkships, and membership in medical honor societies are strongly associated with better performance in clinical, surgical, academic, and overall categories.
View Article and Find Full Text PDF

Purpose: This study investigates how Obstructive sleep apnea (OSA) affects the outcomes of ptosis repair. We hypothesized that patients with OSA have an increased rate of reoperation after ptosis repair.

Methods: This retrospective cohort study included patients age >18 from the Mayo Clinic who underwent ptosis repair by levator advancement or Müller muscle-conjunctiva resection between 2018 and 2021.

View Article and Find Full Text PDF

Objective: The authors report a single-surgeon experience with anterior clinoid meningiomas (ACMs) and propose a novel scoring system to predict visual outcomes based on preoperative risk factors.

Methods: A cohort study of all ACMs that were surgically treated by a single surgeon between 2003 and 2021 was performed. Visual function was assessed by an ophthalmologist pre- and postoperatively.

View Article and Find Full Text PDF

Background: Risk factors for small choroidal melanocytic lesion growth to melanoma have been redefined using multimodal imaging. We explored provider ability to recognize risk factors for small choroidal melanocytic lesion growth to melanoma before and after image-based education and with and without multimodal imaging.

Methods: Providers were invited to participate in a survey assessing ability to identify risk factors for small choroidal melanocytic lesion growth to melanoma using either fundus imaging or multimodal imaging.

View Article and Find Full Text PDF

Background: The transorbital approaches (TOAs) have acquired growing notoriety, thanks to their ability to offer alternative corridors to the skull base. However, the limited access and the unfamiliarity with this surgical perspective make recognition of key landmarks difficult, especially for less experienced surgeons. The study wants to offer a detailed description of the anatomy to comprehend the potential and limitations of TOAs.

View Article and Find Full Text PDF
Article Synopsis
  • Open imaging fluorescence devices using indocyanine green (ICG) have been tested in surgical procedures related to the periorbital area to visualize blood flow and lymphatic drainage.
  • A prospective study conducted from 2021 to 2022 involved 22 patients for ICG angiography and 10 for ICG lymphangiography, successfully showing the vascular supply and lymphatic systems in various surgical contexts.
  • The findings demonstrated that ICG is effective in assessing blood circulation in ocular surgeries and understanding lymphatic pathways, improving surgical outcomes and patient care.
View Article and Find Full Text PDF
Article Synopsis
  • Corticosteroid therapy's effectiveness for thyroid eye disease (TED) is inconsistent, prompting investigation into teprotumumab and tocilizumab as potential alternatives for patients who do not respond to steroids.
  • A study compared 37 patients with steroid-resistant TED (13 on teprotumumab and 6 on tocilizumab) to steroid-naïve patients on similar therapies, analyzing various metrics like proptosis and diplopia over a year.
  • Results showed teprotumumab was generally more effective than tocilizumab in reducing proptosis and resolving diplopia, though both treatments indicated some decline in effectiveness between 24 and 52 weeks.
View Article and Find Full Text PDF

We present clinical and imaging predictors of ocular injuries that required medical management versus surgical intervention in cases of orbital fractures. From 2014 to 2020, a retrospective review of patients with orbital fractures who received ophthalmologic consultation and computed scan (CT) analysis at a level I trauma center was performed. Inclusion criteria were patients with confirmed orbital fracture on CT and ophthalmology consultation.

View Article and Find Full Text PDF

Purpose: To determine treatment outcomes, recurrence rates, and predictors of recurrence, to inform future therapeutic approaches for spheno-orbital meningiomas (SOM).

Methods: A retrospective single-center study of SOM treated from 1990 to 2021 was conducted with comprehensive neuro-ophthalmologic follow-up at Columbia University Medical Center (CUMC). Recurrence requiring reintervention was defined clinically as worsening of visual acuity, visual field defect, or ocular motility after an initial period of stabilization or 6 months of improvement following treatment, or radiologically as either a regrowth with an increase in tumor size by 20% at the site of previous growth or a new region of tumor growth.

View Article and Find Full Text PDF

Purpose: To present 5 cases of alemtuzumab-induced thyroid eye disease (AI-TED) and review the literature to highlight the natural history, severity, and outcomes as compared with conventional thyroid eye disease (TED).

Methods: A multi-institutional retrospective case series of patients with AI-TED was compiled. Chart review evaluated for clinical characteristics, imaging findings, and treatment for AI-TED.

View Article and Find Full Text PDF

There is currently no universally accepted name for inflammatory disease of the eye and orbit associated with thyroid autoimmune disease. Variability in terminology impedes the evaluation of scientific literature and clinical collaboration and can affect patients' understanding of a disease process. The goals of this perspective article are 1.

View Article and Find Full Text PDF
Article Synopsis
  • Middle turbinate resection (MTR) is a surgical procedure often done alongside endonasal sinus surgeries, particularly to enhance the medial orbital wall decompression process.
  • This study examined the effects of MTR on orbital soft-tissue volume, utilizing imaging software to compare pre- and post-surgery CT scans of patients who underwent this procedure.
  • Among five female patients with hyperthyroidism, the results showed that MTR led to an average increase of 0.83 cc in orbital soft tissue volume without any postoperative complications, suggesting its effectiveness in improving surgical outcomes.
View Article and Find Full Text PDF

Purpose: To review clinical presentations of periocular sebaceous carcinoma (SC) and introduce standardized nomenclature for multicentric and multifocal disease presentation.

Methods: A comprehensive PubMed/Medline search was conducted to identify all articles reporting periocular multicentric or multifocal SC presentations. The authors also highlight an additional case of SC presenting with 2 clinically distinct tumor foci and complete secondary invasion of the lacrimal gland.

View Article and Find Full Text PDF
Article Synopsis
  • A 67-year-old man with multiple health issues experienced severe left eye problems, including orbital pain and vision loss, and was diagnosed with left orbital apex syndrome with optic nerve involvement.
  • The MRI showed significant changes in the optic nerve and surrounding areas, but initial treatments and tests yielded no conclusive results.
  • Five months later, he returned with new symptoms, and further imaging revealed a high-grade glioblastoma affecting both optic nerves and the suprasellar region, highlighting the importance of molecular profiling for better diagnosis and potential treatments.
View Article and Find Full Text PDF