Publications by authors named "Andrea Sposato"
Vertebrate spermatogonial stem cells maintain sperm production over the lifetime of an animal, but fertility declines with age. Although morphological studies have informed our understanding of typical spermatogenesis, the molecular and cellular mechanisms underlying the maintenance and decline of spermatogenesis are not yet understood. We used single-cell RNA sequencing to generate a developmental atlas of the aging zebrafish testis.
View Article and Find Full Text PDFVertebrate spermatogonial stem cells maintain sperm production over the lifetime of an animal but fertility declines with age. While morphological studies have greatly informed our understanding of typical spermatogenesis, the molecular and cellular mechanisms underlying spermatogenesis are not yet understood, particularly with respect to the onset of fertility. We used single-cell RNA sequencing to generate a developmental atlas of the zebrafish testis.
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- The study investigates the use of lung ultrasound as a diagnostic and prognostic tool for patients with suspected COVID-19, focusing on its accuracy and effectiveness.
- Conducted with 159 patients in an Emergency Medicine Unit, results showed a higher mortality rate and severity index in COVID-19 patients compared to non-COVID-19 patients.
- The Lung Ultrasound Severity Index demonstrated a good ability to distinguish between COVID-19 positive and negative cases, as well as to predict in-hospital mortality, suggesting it's valuable for diagnosing and identifying at-risk patients.