Publications by authors named "Andrea Spangaro"

Article Synopsis
  • COVID-19 vaccines have been linked to rare instances of acute myocarditis, with rates ranging from 1 in 10,000 to 1 in 100,000, varying by age, sex, and vaccine type.
  • A small percentage (2-4%) of these cases progress to fulminant myocarditis (FM), which can lead to serious complications and has a mortality rate of approximately 1%.
  • The review of 40 FM cases revealed that patients were generally older and predominantly female, occurring more frequently after the first vaccine dose compared to non-fulminant myocarditis cases.
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Article Synopsis
  • There is a known link between cancer and problems with blood clotting, making treatment decisions difficult for healthcare providers, especially for cancer patients with atrial fibrillation (AF).
  • Many cancer patients with AF (about 50%) do not receive oral anticoagulation (OAC) therapy, which is crucial for managing clotting risks.
  • Research indicates that direct oral anticoagulants (DOACs) generally show similar or better safety and efficacy outcomes compared to vitamin K antagonists (VKAs) like warfarin, making DOACs a potentially better option for cancer patients with non-valvular AF.
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(1) Introduction: Cancer and atrial fibrillation (AF) are increasingly coexisting medical challenges. These two conditions share an increased thrombotic and bleeding risk. Although optimal regimens of the most suitable anti-thrombotic therapy are now affirmed in the general population, cancer patients are still particularly understudied on the matter; (2) Aims And Methodology: This metanalysis (11 studies (incl.

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Background: Renal impairment is associated with worse in-hospital and long-term outcomes after coronary artery revascularization, yet limited evidence is available on its impact on short- and long-term outcomes after chronic total occlusion (CTO) percutaneous coronary intervention (PCI).

Methods: We conducted a systematic review of the literature and subsequent random-effect meta-analysis according to the Preferred Reporting Items for Systematic Reviews and Meta Analyses (PRISMA) statement to evaluate the effect of chronic kidney disease (CKD), defined as estimated glomerular filtration rate < 60 ml/min/1.73 m, on CTO PCI.

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Background: Severe aortic stenosis (AS) is often associated with ascending aorta dilation (AAD). AAD is amenable to surgical correction combined with aortic valve replacement. Transcatheter aortic valve implantation (TAVI) might represent a valid therapeutic option in these patients when AAD correction Is not indicated.

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