Publications by authors named "Andrea Schertzer"

Article Synopsis
  • A tuberculosis outbreak in Qikiqtarjuaq Nunavut led to community-wide screening (CWS) initiated by local leaders and the territorial government, aiming to evaluate its cost-effectiveness despite high medical service costs in the Arctic.
  • A hybrid decision analysis and Markov model was used to analyze the impact of CWS compared to no screening over a 20-year period, revealing that CWS results in health gains by preventing active TB cases.
  • The study concluded that while CWS incurs increased costs, it is highly cost-effective, with a low incremental cost-effectiveness ratio of $25.10 per quality adjusted life year (QALY) gained, supporting its use during TB outbreaks in remote communities.*
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Background: The spread of SARS-CoV-2 has been studied at unprecedented levels worldwide. In jurisdictions where molecular analysis was performed on large scales, the emergence and competition of numerous SARS-CoV-2lineages have been observed in near real-time. Lineage identification, traditionally performed from clinical samples, can also be determined by sampling wastewater from sewersheds serving populations of interest.

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In British Columbia, Canada, initial growth of the SARS-CoV-2 Delta variant was slower than that reported in other jurisdictions. Delta became the dominant variant (>50% prevalence) within ≈7-13 weeks of first detection in regions within the United Kingdom and United States. In British Columbia, it remained at <10% of weekly incident COVID-19 cases for 13 weeks after first detection on March 21, 2021, eventually reaching dominance after 17 weeks.

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Head injury accounts for 29% of all traumatic deaths in children. Sepsis is significantly associated with an increased risk of mortality in adult traumatic brain injury patients. In the pediatric population, this relationship is not well understood.

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