Evolution of Specific Phages Infecting the Fish Pathogen .

Background: is the causative agent of the bacterial cold-water disease and rainbow trout fry syndrome. Owing to the issues associated with increasing use of antibiotics to control the diseases, phage therapy has been proposed as an alternative method to control infection within the industry.

Materials And Methods: We explored two simple and fast strategies for the isolation of evolved phages, using three well-characterized phages FpV4, FpV9, and FPSV-S20.