Association of binge eating behavior and psychiatric comorbidity in ELSA-Brasil study: Results from baseline data.

Objective: To estimate the association of binge eating behavior (BE) with common mental disorders (CMD).

Method: Cross sectional investigation of 14,088 adults, aged 35-74years (ELSA-Brasil study). BE was assessed with Structured Clinical Interview for DSM Disorders (SCID - DSM IV) questions, and psychiatric morbidity with CIS-R (CIS R - Clinical Interview Schedule Revised).

Eating disorders symptoms in pregnancy and postpartum: a prospective study in a disadvantaged population in Brazil.

Objective: To assess eating disorder symptoms (EDS) from prepregancy through postpartum.

Method: Seven hundred and twelve women with gestational age ranging from 16th to 36th week completed the eating disorder examination questionnaire (EDE-Q). A shortened version of the EDE-Q was used to assess, retrospectively, EDS during the last 28 days of the pregestational period.

Bereavement and common mental disorders in middle-aged adults: results from the Brazilian longitudinal study of adult health (ELSA-Brasil).

Background: Although bereavement is accompanied with depression and anxiety symptoms, it is usually not associated with increased rates of mental disorders in North American and European samples. Data from low- and middle-income countries are, however, scarce. We therefore explored the prevalence of mental disorders after bereavement in Brazil.

Dietary patterns during pregnancy and the association with sociodemographic characteristics among women attending general practices in southern Brazil: the ECCAGe Study.

The assessment of the relationship between food intake and sociodemographic factors is crucial for developing effective public health policies. The present study aimed to examine dietary patterns in pregnant women and the association between these patterns and sociodemographic characteristics. Pregnant women attending general practices in southern Brazil (n = 712) answered a questionnaire and a food-frequency questionnaire with 88 items.

Binge eating during pregnancy and birth outcomes: a cohort study in a disadvantaged population in Brazil.

Objective: To assess the impact of binge eating behavior (BE) during pregnancy on birth outcomes among 697 Brazilian women who attended primary care.

Method: Pregnant women answered a questionnaire on sociodemographic data, obstetric history, and The Eating Disorder Examination Questionnaire (EDE-Q). Perinatal outcomes were obtained from birth records.

[Mental disorders in a sample of pregnant women receiving primary health care in Southern Brazil].

The aim of this study was to examine the prevalence of probable psychiatric disorders diagnosed during pregnancy and related sociodemographic causative factors among 712 women between the 16th and 36th week of pregnancy receiving prenatal care in 18 basic health units in Porto Alegre and Bento Gonçalves in southern Brazil. PRIME-MD was used to assess mental disorders. The prevalence of probable mental disorder occurred in 41.

Association of candidate genes with phenotypic traits relevant to anorexia nervosa.

This analysis is a follow-up to an earlier investigation of 182 genes selected as likely candidate genetic variations conferring susceptibility to anorexia nervosa (AN). As those initial case-control results revealed no statistically significant differences in single nucleotide polymorphisms, herein, we investigate alternative phenotypes associated with AN. In 1762 females, using regression analyses, we examined the following: (i) lowest illness-related attained body mass index; (ii) age at menarche; (iii) drive for thinness; (iv) body dissatisfaction; (v) trait anxiety; (vi) concern over mistakes; and (vii) the anticipatory worry and pessimism versus uninhibited optimism subscale of the harm avoidance scale.

Association study of 182 candidate genes in anorexia nervosa.

We performed association studies with 5,151 SNPs that were judged as likely candidate genetic variations conferring susceptibility to anorexia nervosa (AN) based on location under reported linkage peaks, previous results in the literature (182 candidate genes), brain expression, biological plausibility, and estrogen responsivity. We employed a case-control design that tested each SNP individually as well as haplotypes derived from these SNPs in 1,085 case individuals with AN diagnoses and 677 control individuals. We also performed separate association analyses using three increasingly restrictive case definitions for AN: all individuals with any subtype of AN (All AN: n = 1,085); individuals with AN with no binge eating behavior (AN with No Binge Eating: n = 687); and individuals with the restricting subtype of AN (Restricting AN: n = 421).

Life beyond the eating disorder: education, relationships, and reproduction.

Objective: We investigated the sociodemographic characteristics in women with and without lifetime eating disorders.

Method: Participants were from a multisite international study of eating disorders (N = 2,096). Education level, relationship status, and reproductive status were examined across eating disorder subtypes and compared with a healthy control group.

Violence and depressive symptoms during pregnancy: a primary care study in Brazil.

Aim: To estimate the prevalence of violence, depressive symptoms, and associated factors during pregnancy in women attending antenatal care in Brazil.

Methods: Violence was assessed using a modified version of the abuse assessment screen (ASS), and depressive symptoms were evaluated using the primary care evaluation of mental disorders (PRIME-MD). Participants were pregnant women attending 18 primary care units in Rio Grande do Sul, Brazil, between June 2006 and April 2007.

Substance use disorders in women with anorexia nervosa.

Objective: We examined prevalence of substance use disorders (SUD) in women with: (1) anorexia nervosa (AN) restricting type (RAN); (2) AN with purging only (PAN); (3) AN with binge eating only (BAN); and (4) lifetime AN and bulimia nervosa (ANBN). Secondary analyses examined SUD related to lifetime purging behavior and lifetime binge eating.

Method: Participants (N = 731) were drawn from the International Price Foundation Genetic Studies.

Sexual functioning in women with eating disorders.

Objective: To describe sexual functioning in women with eating disorders.

Method: We assessed physical intimacy, libido, sexual anxiety, partner status, and sexual relationships in 242 women from the International Price Foundation Genetic Studies relative to normative data.

Results: Intercourse (55.

Lifetime substance abuse, family history of alcohol abuse/dependence and novelty seeking in eating disorders: comparison study of eating disorder subgroups.

Aim: To assess lifetime substance abuse, family history of alcohol abuse/dependence, and novelty seeking in three different eating disorder groups (anorexia nervosa-restrictive; anorexia nervosa-binge eating/purging; anorexia nervosa to bulimia nervosa).

Method: A total sample of 371 eating disorder patients participated in the current study. Assessment measures included the prevalence of substance abuse and family history of alcohol abuse/dependence as well as the novelty-seeking subscale of the Temperament and Character Inventory-Revised.

The Genetics of Anorexia Nervosa: Current Findings and Future Perspectives.

Anorexia nervosa is a perplexing illness with the highest mortality rate of any psychiatric disease. In this paper, we review the genetic research on anorexia nervosa (AN). Family studies have demonstrated that anorexia nervosa is familial, and twin studies have indicated that additive genetic factors contribute to the familial aggregation.

Inappropriate eating behaviors during pregnancy: prevalence and associated factors among pregnant women attending primary care in southern Brazil.

Objective: To examine the prevalence of inappropriate eating behaviors and associated factors among pregnant women in primary care.

Method: The Eating Disorder Examination Questionnaire was used to assess eating disorders and the Primary Care Evaluation of Mental Disorders was used to examine anxiety and depressive symptoms. Body mass index (BMI) and pregestational weight were also assessed.

Temporal patterns of recovery across eating disorder subtypes.

Objective: To compare patterns of recovery in individuals with index episodes of anorexia nervosa (AN) and bulimia nervosa (BN).

Method: Using Kaplan-Meier methods and Cox proportional hazards models, comparisons were conducted that were conditional on duration of eating disorder from onset and included a conservative recovery criterion of 3 asymptomatic years. Data collection was retrospective and from two of the international Price Foundation genetic studies on 901 individuals with eating disorders.

An empirical study of the typology of bulimic symptoms in young Portuguese women.

Objective: To investigate whether clusters of bulimic symptoms exist in a community sample of young Portuguese women.

Method: A total of 2028 females, aged 12-23 years, completed the Eating Disorder Examination Questionnaire (EDE-Q). Latent class analysis was applied to the seven bulimic symptoms, age, and body mass index.

Impulse control disorders in women with eating disorders.

We compared symptom patterns, severity of illness, and comorbidity in individuals with eating disorders with and without impulse control disorders (ICD), and documented the temporal pattern of illness onset. Lifetime ICD were present in 16.6% of 709 women with a history of eating disorders.

Patterns of menstrual disturbance in eating disorders.

Objective: To describe menstrual disturbance in eating disorders (ED).

Method: We describe menstrual history in 1,705 women and compare eating, weight, and psychopathological traits across menstrual groups.

Results: Menstrual dysfunction occurred across all eating disorder subtypes.

AKT1 and neurocognition in schizophrenia.

Objective: Previous research has shown conflicting results for the significance of five v-akt murine thymoma viral oncogene homolog 1 (AKT1) single-nucleotide polymorphisms (SNPs) to the aetiology of schizophrenia. Neurocognition is a plausible endophenotype for schizophrenia and it was reasoned that the lack of agreement might be due to variability in neurocognition across studies. Therefore, the association of genetic variation in AKT1 with neurocognition was investigated in patients with schizophrenia.

Symptom profile of major depressive disorder in women with eating disorders.

Objective: Based on the well-documented association between eating disorders (EDs) and affective disorders, the patterns of comorbidity of EDs and major depressive disorder (MDD) were investigated. The temporal relation between EDs and MDD onset was analyzed to determine differences in the course and nature of MDD when experienced prior to versus after the onset of the ED.

Method: Lifetime MDD and depressive symptoms were assessed in 1371 women with a history of ED.

[Genetics in eating disorders: extending the boundaries of research].

Objective: To review the recent literature relevant to genetic research in eating disorders and to discuss unique issues which are crucial for the development of a genetic research project in eating disorders in Brazil.

Method: A computer literature review was conducted in the Medline database between 1984 and may 2005 with the search terms "eating disorders", "anorexia nervosa", "bulimia nervosa", "binge eating disorder", "family", "twin" and "molecular genetic" studies.

Results: Current research findings suggest a substantial influence of genetic factors on the liability to anorexia nervosa and bulimia nervosa.

Body dissatisfaction in Brazilian schoolchildren: prevalence and associated factors.

Objective: To examine the prevalence of body dissatisfaction and associated factors in 8- to 11-year-old schoolchildren.

Methods: A cross-sectional study including children aged 8- to 11-years enrolled in public and private schools in Porto Alegre, Southern Brazil, was carried out from August to December, 2001. A total of 901 subjects were selected through cluster sampling.

Who are the children with adequate weight who feel fat?

Objective: To measure the prevalence of children with adequate weight who feel fat and to examine the factors associated with this perception.

Methods: Cross-sectional study with 901 schoolchildren aged 8-11 years selected by cluster sampling. The children had their weight and height measured, and answered a questionnaire that included a self-esteem scale and questions on self-perception of weight, and perception of parents' and friends' expectations regarding the child's weight.