Skull Base Dural Thickness and Relationship to Demographic Features: A Postmortem Study and Literature Review.

Dural membrane is an important anatomic structure that surrounds and protects the entire central nervous system. Physical properties of the dura have many pathophysiological and therapeutic implications in cranial surgery, especially skull base disorders. The aim of this study is to investigate variation in skull base dural thickness and correlation with different demographic parameters.

The hybrid lid crease approach to address lateral frontal sinus disease with orbital extension.

Objective: This study aimed to describe the hybrid lid crease approach in conjunction with functional endoscopic sinus surgery (FESS) for lateral frontal sinus disease with orbital extension.

Study Design: Retrospective case review.

Methods: Patients undergoing hybrid lid crease approach with FESS for frontal sinus disease were reviewed retrospectively.

The effect of geniglossal advancement on airway flow using a computational flow dynamics model.

Objectives/hypothesis: Obstructive sleep apnea (OSA) is a sleep disorder caused by partial or complete collapse of the pharyngeal airway. Genioglossal advancement (GGA) is a well-tolerated surgical procedure intended to address hypopharyngeal collapse, yet there are few studies that monitor changes in airflow dynamics at this site. Computation fluid dynamics (CFD) utilizes airflow simulation to predict changes in airflow after anatomic manipulation.

Adenoviral gene transfer corrects the ion transport defect in the sinus epithelia of a porcine CF model.

Cystic fibrosis (CF) pigs spontaneously develop sinus and lung disease resembling human CF. The CF pig presents a unique opportunity to use gene transfer to test hypotheses to further understand the pathogenesis of CF sinus disease. In this study, we investigated the ion transport defect in the CF sinus and found that CF porcine sinus epithelia lack cyclic AMP (cAMP)-stimulated anion transport.

Sinus hypoplasia precedes sinus infection in a porcine model of cystic fibrosis.

Objectives/hypothesis: Chronic sinusitis is nearly universal in humans with cystic fibrosis (CF) and is accompanied by sinus hypoplasia (small sinuses). However, whether impaired sinus development is a primary feature of loss of the cystic fibrosis transmembrane conductance regulator (CFTR) or a secondary consequence of chronic infection remains unknown. Our objective was to study the early pathogenesis of sinus disease in CF.

Retrograde sialendoscopy: a new technique for avoiding retained ductal stones.

Objectives: Recurrent infection from stones retained in Wharton's duct after submandibular gland resection warrants intraoperative attention to the duct remnant. Our hypothesis was that retrograde sialendoscopy would help ensure complete stone removal in submandibular gland removal for sialolithiasis.

Methods: We reviewed 9 sequential cases of submandibular sialolithiasis treated surgically via open procedures at a tertiary care center by a single surgeon between November 2007 and December 2009.

Successful reconstruction of scalp and skull defects: lessons learned from a large series.

Objective: To provide a framework for the management of scalp and skull defects.

Design: Retrospective chart review.

Setting: Two tertiary care hospitals.

Continued alcohol use in patients with head and neck cancer.

Background: The effect of posttreatment alcohol consumption on health-related quality of life (QOL) and factors predicting overall QOL and continued alcohol consumption were examined in patients with head and neck cancer.

Methods: Self-reported alcohol use and abuse 1 year after diagnosis was analyzed.

Results: Although current drinkers (44.