RNA-Binding Proteins: A Role in Neurotoxicity?

Despite sustained efforts to treat neurodegenerative diseases, little is known at the molecular level to understand and generate novel therapeutic approaches for these malignancies. Therefore, it is not surprising that neurogenerative diseases are among the leading causes of death in the aged population. Neurons require sophisticated cellular mechanisms to maintain proper protein homeostasis.

New Insights into the Toxin Diversity and Antimicrobial Activity of the "Fire Coral" .

To date, few studies have been carried out aimed at characterizing the toxins synthesized by hydrocorals of the genus . The purpose of this study was to explore the toxin diversity and antibacterial activity of the "fire coral" using a transcriptomic data mining approach. In addition, the cytolytic and antibacterial activities of the nematocyst proteome were experimentally confirmed.

Comparative Analysis of the Soluble Proteome and the Cytolytic Activity of Unbleached and Bleached ("Fire Coral") from the Mexican Caribbean.

Coral bleaching caused by global warming has resulted in massive damage to coral reefs worldwide. Studies addressing the consequences of elevated temperature have focused on organisms of the class Anthozoa, and up to now, there is little information regarding the mechanisms by which reef forming Hydrozoans face thermal stress. In this study, we carried out a comparative analysis of the soluble proteome and the cytolytic activity of unbleached and bleached ("fire coral") that inhabited reef colonies exposed to the 2015-2016 El Niño-Southern Oscillation in the Mexican Caribbean.