Publications by authors named "Andrea Navarro Torres"
Article Synopsis
- The study addresses the difficulty of understanding how specific sequences in the genome relate to their functions, especially with limited tools for hypermutation.
- A new platform called helicase-assisted continuous editing (HACE) is introduced, which uses CRISPR-Cas9 to induce mutations over large sections of the genome effectively.
- HACE has been applied to study mutations related to drug resistance and missplicing, and it offers a robust way to explore both coding and noncoding genetic variants to better understand their roles in biological functions.
Noninvasive monitoring of biofabricated tissues during the biomanufacturing process is needed to obtain reproducible, healthy, and functional tissues. Measuring the levels of biomarkers secreted from tissues is a promising strategy to understand the status of tissues during biofabrication. Continuous and real-time information from cultivated tissues enables users to achieve scalable manufacturing.
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