Correlation of Anti-Müllerian hormone serum concentration measured in proestrus and estrus with the litter size as a fertility marker in bitches.

The use of the anti-Müllerian hormone (AMH) serum concentration as a fertility marker has been shown in cows, sheep and mares and has been indicated in one study in female dogs. The aim of this study was to investigate the connection between the AMH serum concentration, taken at two defined time points during the bitch`s heat, and the litter size to investigate whether AMH can be used as a practical measurement for the individual breeding bitch to predict litter size. The study was carried out on 27 healthy female dogs presented for pre-breeding examination, considering all previously known influencing factors on AMH in the bitch such as age, body weight and estrous cycle phase at the time the sample was taken.

[Flushing the canine prepuce before mating, useful or not?].

Objective: Various facultative pathogenic bacteria have been detected in the dog's prepuce. To prevent the transmission of these bacteria, some breeders flush the prepuce of their stud dogs before mating. The purpose of this study is to find out whether preputial flushing is medically useful before mating.

The effect of peri- and postoperative antibiotic prophylaxis on surgical site infection in surgeries with elective antibiotic administration.

The aim of this study was to investigate the effect of peri- and postoperative antimicrobial prophylaxis (AMP) on surgical site infection (SSI) in surgeries with elective antibiotic administration in a large university hospital with a high volume of people in the operating room. In this retrospective study, 1060 cats and dogs belonging to private owners were analysed for the occurrence of SSI over a period of almost 5 years, except during the COVID pandemic. Both the patient files were included, and the patient owners were contacted by questionnaire.

[Arthroscopic removal of the fragmented medial coronoid process in dogs - Evaluation of treatment results with special reference to postoperative computed tomography and residual particles].

Objective: The aim of this study was to assess the treatment success of dogs with medial coronoid disease (here: Fragmented Coronoid Process [FCP]) following arthroscopically performed subtotal coronoidectomy by the use of subjective and objective gait analysis and the evaluation of osteoarthritis progression in addition to their correlation with the findings from postoperative computed tomography. In particular, the clinical relevance of residual particles remaining postoperatively was to be evaluated.

Material And Methods: Thirty elbows from 24 dogs of different breeds were examined clinically, orthopedically, using gait analysis as well as radiographically at least 6 months after unilateral or bilateral subtotal coronoidectomy.

Investigation of stress in dogs during an MRI examination in response to hearing protection.

The aim of the present study was to investigate whether the wearing of hearing protection has a positive influence on stress levels during an MRI examination in dogs under anaesthesia. To this end, the stress hormones cortisol and arginine vasopressin (AVP) were measured in the saliva of patients wearing hearing protection during an MRI scan, as well as in the control group without hearing protection, before and after the scan. Pulse rate and noise level were also measured during the MRI.

Efficacy of a Single Injection of Stromal Vascular Fraction in Dogs with Elbow Osteoarthritis: A Clinical Prospective Study.

This study aimed to assess the efficacy of a single intra-articular injection of autologous stromal vascular fraction (SVF) in dogs with chronic lameness due to advanced elbow osteoarthritis (OA) that were unresponsive to conventional drug therapy. In this clinical, prospective, non-blinded, single-center study, twenty-three dogs received autologous SVF derived from falciform adipose tissue. Primary outcome measures over the six-month study period included clinical-orthopedic and radiographic examinations, objective gait analysis and validated owner questionnaires.

The oral intake of specific Bioactive Collagen Peptides (BCP) improves gait and quality of life in canine osteoarthritis patients-A translational large animal model for a nutritional therapy option.

Objective: Osteoarthritis (OA) is the most common joint disorder in humans and dogs. Due to its chronic progressive nature, the predominant clinical signs after a certain point are pain and immobility. The similar pathogenesis allows conclusions to be drawn from canine to human OA.

Physiological Anti-Müllerian Hormone Concentrations in Male and Female Dogs and Cats before and around Puberty.

In recent years several studies established the diagnostic value of anti-Müllerian hormone (AMH) in companion animals. However, less is known about physiological AMH concentrations in young individuals highlighting the necessity to apply the diagnostic findings to this group. The aim of this study was to determine the AMH values of healthy male and female dogs between the age of 8 and 48 weeks, tomcats under 8 weeks and up to 48 weeks of age and queens between 2 to 12 weeks of age.

Salivary cortisol measurements in brachycephalic dog breeds as part of a standardized stress test.

Introduction: Brachycephalic obstructive airway syndrome (BOAS) is a common condition in brachycephalic dogs, with Pugs (PG) and French Bulldogs (FB) appearing to be particularly typically affected. Objective and easy-to-perform tests are necessary to detect the disease at an early stage and to exclude dogs affected by BOAS from breeding.

Methods: The present study investigated the extent to which vital signs and salivary cortisol concentrations can be used to distinguish between healthy and BOAS-affected dogs in a standardized fitness test.

Studies on the association of malondialdehyde as a biomarker for oxidative stress and degree of malignancy in dogs with mammary adenocarcinomas.

Background: Mammary adenocarcinomas are one of the most common tumour diseases in bitches. The relationship between oxidative stress and the degree of malignancy of the tumour has not been sufficiently researched in veterinary medicine.

Objectives: The main objective was to investigate the potential role of MDA as a practice-relevant biomarker for the assessment of systemic oxidative stress and to determine whether this parameter can indicate the malignancy grade of a mammary adenocarcinoma.

Performance and overview of clinically relevant areas of application of saliva testing in the cat.

Introduction: The cat represents an important model in order to investigate basic physiological knowledge of salivary secretion as well as pharmacokinetics of active substances.

Objective: The aim of the study was to review in which diagnostic application areas saliva testing is routinely used and in which areas it could be further explored in the future.

Materials And Methods: Literature relevant to the research question was collected in March 2022 using the Pubmed database.

Prevalence of osteoarthritis in the shoulder, elbow, hip and stifle joints of dogs older than 8 years.

Osteoarthritis is one of the most common diseases in veterinary medicine. There are various causes for joints developing OA, with some of them being well investigated, while others are still a matter of speculation. In this retrospective study we examined the prevalence of OA in the shoulder, elbow, hip and stifle joints in a clinic population of dogs older than 8 years, which were presented mostly due to orthopaedic complaints.

In Vivo Investigation of 3D-Printed Calcium Magnesium Phosphate Wedges in Partial Load Defects.

Bone substitutes are ideally biocompatible, osteoconductive, degradable and defect-specific and provide mechanical stability. Magnesium phosphate cements (MPCs) offer high initial stability and faster degradation compared to the well-researched calcium phosphate cements (CPCs). Calcium magnesium phosphate cements (CMPCs) should combine the properties of both and have so far shown promising results.

Evaluation of Meniscal Load and Load Distribution in the Sound Canine Stifle at Different Angles of Flexion.

Objectives:  The aim of the study was to investigate the contact mechanics and kinematic changes in the stifle in different standing angles.

Study Design:  We performed a biomechanical study using pairs of canine cadaver hindlimbs. Motion sensors were fixed to the tibia and the femur for kinematic data acquisition.

Fur Cortisol in French Bulldogs with Different Manifestations of Brachycephalic Obstructive Airway Syndrome.

In the present study, 33 French bulldogs with varying degrees of brachycephalic obstructive airway syndrome (BOAS) were evaluated for various parameters to provide evidence of chronic stress in the dogs. For this purpose, an owner interview, a clinical examination, and cortisol concentrations in the fur of the dogs were collected. The median cortisol concentration in the fur of the dogs suffering from BOAS (n = 19) was 0.

3D Slicer open-source software plug-in for vector-based angle calculation of canine hind limb alignment in computed tomographic images.

Background: Severe and complex angular limb deformities in dogs require accurate morphological assessment using diagnostic imaging to achieve successful orthopedic surgery. Computed tomography (CT) is commonly used to overcome projection errors in two-dimensional angular measurements of dog hindlimb alignment. Three-dimensional volume rendering (VR) techniques permit virtual positioning and variable projection, but the final CT-image that defines the projection plane for angular measurements remains two-dimensional.

Arthrographic description of the canine carpal joint cavities and its recesses.

Joint effusion is diagnostically important. The canine carpal joint effusion, which is sometimes difficult to detect clinically, has received less attention in diagnostic ultrasound (US) studies. The aim of the present study was to provide a description of the morphological appearance of the canine carpal joint cavities and recesses using US, radiography, helical computed tomography (CT) and three-dimensional volume rendering technique (3D-VRT) images and to prove the applicability of musculoskeletal US for the detection of artificial carpal joint effusion in dogs.

Microcomputed tomographic analysis of the ulnar trochlear notch in medium- and large-breed canine cadavers with and without medial coronoid disease.

Medial coronoid disease (MCD) is a common disease often associated with thoracic limb lameness in medium- and large-breed dogs. The term MCD includes subchondral changes of the medial coronoid process (MCP), as well as pathologies of both cartilaginous surfaces. As there are only a few comprehensive and detailed studies on the trabecular structure of the medial coronoid, the goal of this study was to compare the trabecular structure of the ulnar trochlear notch of canine cadavers with and without MCD using different micro-computed tomographic (micro-CT) parameters.

Therapeutic success in fragmented coronoid process disease and other canine medial elbow compartment pathology: a systematic review with meta-analyses.

Introduction: The correct treatment of elbow dysplasia is controversial in modern small animal orthopedics. The aim of this study was to compile all relevant literature of the therapy of fragmented coronoid process and other hereditary disorders of the medial elbow compartment and to statistically evaluate the therapeutic results in three meta-analyses.

Methods: The basis for the systematic literature review was a comprehensive database search of Web of Science, PubMed and Medline.

Influence of Femoral Position and Pelvic Projection on Norberg Angle Measurements.

Objective:  Canine hip dysplasia is a common orthopaedic disease in dogs. The Norberg angle value is a measure of hip joint laxity. The aim of this study was to quantify the degree of rotation necessary to consider the radiograph as inadequately positioned and to determine the influence of rotation on the Norberg angle.

Comparison of CT-measured angles of pelvic limbs without patellar luxation of six canine breeds.

Introduction: Dogs with medial patellar luxation can be affected by pelvic limb deformities whose corrective osteotomies and associated biomechanical rebalancing might provide higher success rates than standard surgical procedures limited to the stifle joint. In bilaterally affected canine patients, comparison with the contralateral normal limb is impossible. Reference values are useful for orthopedic decision-making.

Three-dimensional computed tomographic angular measurements of the canine tibia using a bone-centered coordinate system.

Introduction: Canine tibial alignment is determined by two-dimensional angular measurements, and tibial torsion is challenging. Aim of the study was the development and evaluation of a CT technique to measure canine tibial varus and torsion angles independent from positioning and truly three-dimensional.

Materials And Methods: A bone-centered 3D cartesian coordinate system was introduced into the CT-scans of canine tibiae and aligned with the anatomical planes of the bone based on osseous reference points.

Meniscal Load and Load Distribution in the Canine Stifle after Modified Tibial Tuberosity Advancement with 9 mm and 12 mm Cranialization of the Tibial Tuberosity in Different Standing Angles.

Objectives:  The aim of this study was to investigate the kinetic and kinematic changes in the stifle after a modified tibial tuberosity advancement (TTA) with 9 and 12 mm cranialization of the tibial tuberosity in different standing angles.

Study Design:  Biomechanical ex vivo study using seven unpaired canine cadaver hindlimbs. Sham TTA surgery was performed.

Computed tomographic angular measurements using a bone-centered three-dimensional coordinate system are accurate in a femoral torsional deformity model and precise in clinical canine patients.

Introduction: In small animal orthopedics, angular measurements in the canine femur are often applied in clinical patients with bone deformities and especially in complex and severe cases. Computed tomography (CT) has been shown to be more precise and accurate than two-dimensional radiography, and several methods are described. Measurement techniques evaluated in normal bones must prove accuracy in deformed bones in clinical settings.

Evaluation of Dental and Oral Pathologies of 36 Captive Lions () and Tigers ().

The documented increase in the occurrence of dental diseases in captive big cats over the past decades has necessitated the need to target dental medical research accordingly. The aim of this study was the systematic evaluation of dental and oral pathologies of lions and tigers which included intraoral dental radiography. Thirty-six animals of both sexes, ranging in age from nine months to 18 years, predominantly in circus husbandry, served as the basis of the present study, and their dental health status was investigated.