Publications by authors named "Andrea Maria Schmidt-Westhausen"

The mucosa of the oral cavity is exposed to a large number of different microorganisms such as archaea, bacteria, fungi, parasites, and viruses. Among those, viruses cause specific infections, which can easily be transmitted from one person to another. The infectious route may not only include patients and their relatives but also the dental professional team.

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Background: The question arises if there is an association of psycho-emotional stress and chronic soft tissue injuries caused by bruxism somatoform disorders with oral squamous cell carcinoma (OSCC).

Methods: Patients with and without "somatoform disorders including psychogenic disturbances" (International Classification of Diseases [ICD]-10 code F45.8), and/or "unspecific behavioral syndromes" (F59), and/or "sleep related bruxism" (G47.

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Article Synopsis
  • Recurrent aphthous stomatitis (RAS) is a common oral condition characterized by painful ulcers, and this study investigates its potential link to oral squamous cell carcinoma (OSCC).
  • The research analyzed data from nearly 25 million individuals over 20 years, comparing 72,845 patients with RAS and a matched group without RAS for differences in OSCC development within five years.
  • Results showed a higher risk of OSCC in patients with RAS (0.65%) compared to those without (0.18%), indicating a significant association, with a relative risk of 3.48.
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Background: Syphilis is an infectious disease that is at least discussed to be premalignant. This potential, combined with its general pathological impact, raises the question if syphilis increases mortality in oral cancer patients. The aim of the study was to assess if the five-year survival rates among patients suffering from oral squamous cell carcinoma (OSCC) with (cohort I) and without association with syphilis (cohort II) differ.

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Introduction: Onset of oral lichenoid lesions (OLL) or oral lichen planus (OLP) can be rare adverse reactions to vaccines. Recently, the first solitary cases were reported after COVID-19 vaccination. The aim of the present study was to assess if an increased frequency of OLL/OLP can be found after COVID-19 vaccination within a large real-world cohort.

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Objectives: The epidemiologic distribution of non-albicans species in the oral cavity of oral lichen planus (OLP) patients remains uncertain. Therefore, the aim of this study was to identify factors associated with the presence of C. dubliniensis and other non-albicans species.

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In recent years, a large number of studies have been published evaluating the therapy of oral lichen planus. In addition to standard medication such as topical glucocorticoid therapy, substances such as Aloe vera, hyaluronic acid, and treatments from traditional Chinese medicine have also been investigated. It is not always easy for dental practitioners to find an adequate therapy according to the clinical picture.

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Background: The objectives of this study were to determine the status of oral health among newly arrived refugees in Germany and to explore their knowledge, attitude and practices on oral hygiene.

Methods: All participants (n = 386) were adults, 18-60 years of age, coming from Syria and Iraq and registered as refugees in Germany within one year prior to the enrollment in the study. Clinical oral assessments in addition to a survey on knowledge, attitude and practice were carried out.

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Objectives: The aim of the study was to investigate whether specific volatile organic compounds (VOCs) can be detected in oral candidiasis patients using breath analysis in order to develop a point-of-care diagnostic tool.

Patients/methods: Breath samples of 10 diseased patients and 10 subjects carrying no Candida spp. were analyzed using gas chromatography and mass spectrometry.

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Objective: The objective of this study was to investigate the effect of topical morphine on erosive/ulcerative lesions in patients with oral lichen planus (OLP). Previous studies reported on an enhanced remission of skin wounds when morphine was applied topically.

Materials And Methods: This was single-center, prospective, double-blind, placebo-controlled, randomized, multi-arm (3), phase II study (RCT).

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Extended use of antimycotics in oral candidiasis therapy gives rise to problems related to fungal drug resistance. The aim of this pilot study was to investigate the efficacy of tissue tolerable plasma (TTP) in denture stomatitis patients. It was hypothesised that (I): erythema and (IIa): complaint remission would be accelerated and (IIb): colony forming unit (CFU) reduction would be improved.

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Oral candidiasis is the most frequent fungal infection of the oral cavity. Clinical diagnoses require mycological confirmation, which is time-consuming in case of culture testing. The aim of the study was to identify signature volatiles to develop a chairside breath test to diagnose oral candidiasis.

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Objectives: In order to identify oral candidiasis patients being at risk of carrying potentially drug-resistant Candida, the aim of the study was to detect local, systemic, demographic, and health-related factors influencing (I) yeast spectrum composition and (II) antifungal administration frequency. Additionally, the aim was to investigate (III) species shift occurrence.

Materials And Methods: Data from 798 patients (496 females, 302 males; mean age 59.

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Surface decontamination remains challenging in peri-implant infection therapy. To investigate the bactericidal efficacy of tissue tolerable plasma, S. mitis biofilms were created in vitro on 32 microrough titanium dental implants.

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Primary stability has a major impact on the long-term success of dental implants. The aim of this study was to investigate the correlation of resonance frequency analysis (RFA) and insertion torque of self-tapping and non-self-tapping implants and their respective differences in primary stability. A group of 263 patients were treated with a total of 602 conically formed dental implants: 408 non-self-tapping Ankylos and 194 self-tapping Camlog.

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Purpose: To report the treatment of facial skin defects by cultured epithelial autografts and its clinical outcome.

Patients And Methods: Between 2002 and 2003, 18 patients with secondary facial skin defects (after tumor excision, trauma, or due to chronic wound healing dysfunction) were successfully treated with autologous cultivated keratinocytes. Overall, 12 patients were included in our study.

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Article Synopsis
  • The use of highly active antiretroviral therapy (HAART) since 1997 has improved the health and life expectancy of HIV-positive patients, making them potential candidates for implant-supported prosthetic rehabilitation.
  • Three case reports describe the successful implant-prosthetic treatments for three HIV-positive patients, with varying therapies and health backgrounds, highlighting that no oral manifestations of HIV were observed during the study.
  • The results indicate that, with careful monitoring, immunologically stable HIV-positive individuals on HAART can safely undergo implant-prosthetic rehabilitation without significant complications.
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In this study, we compared 103 OralCDx results with the histological findings of 96 clinical sites in 80 patients (33 females; 64.3+/-13.7 years and 47 males; 53.

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