Angiogenic factors as prognostic markers in neuroendocrine neoplasms.

Purpose: Angiogenic markers in neuroendocrine neoplasms (NENs) have recently received increasing attention, but their clinical role remains unclear. The aim of this study was to evaluate the role of angiogenic markers in NEN aggressiveness and prognosis.

Methods: We performed a prospective observational study including 46 consecutive patients with proven NENs of pulmonary (45.