Publications by authors named "Andrea Maia Pimentel"
Endoscopic and Histopathological Findings of the Esophagus, Stomach, and Duodenum in Patients with Crohn's Disease from a Reference Center in Bahia, Brazil.
Andrea Maia Pimentel Luiz Antônio Rodrigues de Freitas Rita de Cássia Reis Cruz Isaac Neri de Novais Silva Laíla Damasceno Andrade
Clin Pract
June 2021
Article Synopsis
- - The study aimed to investigate endoscopic and histopathological changes in the esophagus, stomach, and duodenum of Crohn's disease patients through esophagogastroduodenoscopies and biopsies, assessing bacterial presence with Giemsa staining.
- - Out of 58 patients, significant findings included erosive esophagitis in 43.1%, gastritis in 55.2%, and erosive duodenitis in 13.8%, with varying inflammatory activity noted in patients with and without bacterial infection.
- - The findings revealed a prevalence of nonspecific changes linked to Crohn's disease, with rare instances of focally enhanced gastritis, while factors like time since diagnosis, age, and ongoing treatments
Crohn's disease with involvement of the esophagus, stomach and duodenum has a prevalence of 0.5% to 4% in symptomatic adult patients, but some studies have shown that these results may be underestimated, since upper gastrointestinal endoscopy is not performed routinely in the initial evaluation of the disease in adult patients, as it is in the pediatric population. In general, involvement of the upper gastrointestinal tract in Crohn's disease occurs concomitantly with involvement of the lower gastrointestinal tract.
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