Evaluation of the cataractogenic effect of viscoanesthetic solutions on the rabbit crystalline lens.

Purpose: To evaluate the toxicity and cataractogenic effect of solutions combining sodium (Na) hyaluronate 1.0% and 1.5% with lidocaine 1.

Posterior capsule opacification in rabbit eyes implanted with 1-piece and 3-piece hydrophobic acrylic intraocular lenses.

Purpose: To evaluate the outcome of posterior capsule opacification (PCO) after implantation in rabbit eyes of currently available 3-piece and 1-piece hydrophobic acrylic intraocular lenses (IOLs) with square optic edges.

Setting: John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA.

Analysis of the capsule edge after Fugo plasma blade capsulotomy, continuous curvilinear capsulorhexis, and can-opener capsulotomy.

Purpose: To compare the quality of the edges of anterior capsulotomies performed in porcine eyes using 3 different techniques.

Setting: David J. Apple, MD Laboratories for Ophthalmic Devices Research, John A.

Late postoperative opacification of a hydrophilic acrylic (hydrogel) intraocular lens: a clinicopathological analysis of 106 explants.

Purpose: To report clinical, pathologic, histochemical, ultrastructural, and spectroscopic analyses of MemoryLens intraocular lenses (IOLs) explanted from patients who had visual disturbances caused by postoperative opacification of the lens optic.

Design: Noncomparative, large case series with clinicopathologic correlation.

Participants: A total of 106 hydrophilic acrylic IOLs of the same design explanted from 106 different patients.

Posterior capsule opacification in rabbit eyes implanted with hydrophilic acrylic intraocular lenses with enhanced square edge.

Purpose: To evaluate the development of posterior capsule opacification (PCO) after implantation of single-piece hydrophilic acrylic intraocular lenses (IOLs) with an enhanced square edge.

Setting: John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA.

Capsulorhexis ovaling and capsular bag stretch after rigid and foldable intraocular lens implantation: experimental study in pediatric human eyes.

Purpose: To compare the amount of capsulorhexis ovaling and capsular bag stretch produced by various intraocular lenses (IOLs) implanted in pediatric human eyes obtained post-mortem.

Setting: David J. Apple, MD Laboratories for Ophthalmic Devices Research, John A.

Correlation between different measurements within the eye relative to phakic intraocular lens implantation.

Purpose: To obtain measurements of the white-to-white distance and the anterior chamber and ciliary sulcus diameters in phakic human eyes obtained post-mortem to find a correlation between these measurements.

Setting: David J. Apple, MD Laboratories for Ophthalmic Devices Research, John A.

Pathological evaluation of postmortem human eyes implanted with a new single-piece hydrophobic acrylic lens.

Purpose: To report the pathological findings in 14 human cadaver eyes implanted with a single-piece AcrySof(Alcon Laboratories) posterior chamber intraocular lens (IOL).

Setting: David J. Apple, MD Laboratories for Ophthalmic Devices Research, John A.

Single-piece hydrophobic acrylic intraocular lens explanted within the capsular bag: case report with clinicopathological correlation.

A 74-year-old woman had uneventful phacoemulsification with implantation of a single-piece hydrophobic acrylic intraocular lens (IOL) (SA30AL) in her left eye. Two weeks after the surgery, the patient presented for ophthalmological consultation reporting pseudophakic dysphotopsia, which she had subjectively noted since surgery. Explantation/exchange of the IOL was performed 3 months after the surgery.

Capsular bag opacification after experimental implantation of a new accommodating intraocular lens in rabbit eyes.

Purpose: To evaluate the development of capsular bag opacification in rabbit eyes after implantation of an intraocular lens (IOL) designed to minimize contact between the anterior capsule and the IOL and ensure expansion of the capsular bag.

Setting: David J. Apple, MD Laboratories for Ophthalmic Devices Research, John A.

Sir Nicholas Harold Ridley. He changed the world, so that we might better see it.

Cataract surgery with intraocular lens (IOL) implantation has become the most common and most successful of all operations in medicine. Sir Harold Ridley's first cataract extraction with implantation of an IOL marked the beginning of a major change in the practice of ophthalmology. Millions of patients worldwide have benefited from Sir Ridley's invention, and are likely to continue to derive benefit from this device.

Implantation of a single-piece, hydrophilic, acrylic, minus-power foldable posterior chamber intraocular lens in a rabbit model: clinicopathologic study of posterior capsule opacification.

Purpose: To compare the extent of posterior capsule opacification (PCO) after implantation of a standard-power biconvex Centerflex intraocular lens (IOL) and a newly introduced biconcave high-minus-power Centerflex design in rabbit eyes.

Setting: The Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, and the David J. Apple, MD, Laboratories for Ophthalmic Devices Research, John A.

Management of bipseudophakia with implantation of an iris claw lens.

We discuss a case of bipseudophakia with secondary dislocation of a posterior chamber intraocular lens (IOL) into the anterior chamber that was managed by explantation of the anterior and posterior chamber IOLs and implantation of an iris claw IOL.

Opacification of two hydrophilic acrylic intraocular lenses 3 months after implantation.

Background And Objective: To report clinical, pathologic, histochemical, ultrastructural, and spectrographic analyses of explanted hydrophilic acrylic intraocular lenses (IOLs) obtained from two patients who had early visual disturbances caused by postoperative opacification of the lens optic.

Materials And Methods: Two hydrophilic IOLs were explanted from patients with decreased visual acuity. The patients became symptomatic 3 months after uneventful phacoemulsification and lens implantation.

Viscoanesthesia. Part III: removal time of OVD/viscoanesthetic solutions from the capsular bag of postmortem human eyes.

Purpose: To investigate and evaluate the removal time of various ophthalmic viscosurgical device (OVD)/viscoanesthetic solutions containing sodium hyaluronate 1.5% with different concentrations of lidocaine (0.5%, 1.

Viscoanesthesia. Part II: toxicity to intraocular structures after phacoemulsification in a rabbit model.

Purpose: To investigate the toxicity of a solution that combines sodium hyaluronate 1.5% with lidocaine (0.5%, 1.

Viscoanesthesia. Part I: toxicity to corneal endothelial cells in a rabbit model.

Purpose: To evaluate the toxicity of a solution combining sodium hyaluronate 1.5% with lidocaine (0.5%, 1.

Scanning electron microscopic and histologic evaluation of the AcrySof SA30AL acrylic intraocular lens. Manufacturing quality and morphology in the capsular bag.

Purpose: To evaluate the properties of the AcrySof(R) SA30AL (Alcon Laboratories, Inc.) single-piece foldable posterior chamber intraocular lens (IOL).

Setting: Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA.

Silicone plate-haptic posterior chamber intraocular lens implanted in the anterior chamber: report of a bilateral case and potential complications.

Background And Objective: To evaluate possible complications associated with implantation of a posterior chamber (PC) intraocular lens (IOL) in the anterior chamber.

Materials And Methods: We analyzed a plate-haptic silicone IOL that had been explanted from the anterior chamber of an 83-year-old female. Additionally, the lens was experimentally reimplanted into the anterior chambers of 3 human cadaver eyes.

Aqueous infiltration into an implantable miniaturized telescope.

The implantable miniaturized telescope (IMT) is the first intraocular magnifying system proposed for optical correction in patients with age-related macular degeneration (ARMD). The optical component is embedded in a carrying device designed as an intraocular lens that is implanted after cataract surgery. In this study, we report findings on an IMT that was explanted because of aqueous infiltration into its optic and describe the configuration of this device and the surgical technique required for its implantation.

Permanent blue discoloration of a hydrogel intraocular lens by intraoperative trypan blue.

A 79-year-old white man had cataract surgery in the right eye with implantation of an Acqua intraocular lens (IOL) (Mediphacos). Trypan blue 0.1% was used during surgery to stain the anterior capsule and enhance the contrast during capsulorhexis.

Loop memory of haptic materials in posterior chamber intraocular lenses.

Purpose: To compare the shape recovery ratios after compression of haptic materials used in the manufacture of intraocular lenses (IOLs).

Setting: Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA.

Methods: The loop memory of 40 silicone-optic posterior chamber IOLs was studied.

Bipseudophakia. Clinicopathological findings of a pseudophakic human globe obtained postmortem implanted with an anterior chamber and a posterior chamber intraocular lens.

We report the clinicopathological findings of a human pseudophakic globe obtained postmortem, containing both anterior and posterior chamber intraocular lens, a condition we termed "bipseudophakia".

Bipseudophakia: clinicopathological correlation of a dropped lens.

Purpose: To examine postmortem human globes containing an anterior chamber and a posterior chamber intraocular lens (IOL).

Setting: Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Charleston, South Carolina, USA.

Methods: The globes were sectioned at the equator, and the anterior and posterior segments were macroscopically examined.