Publications by authors named "Andrea Leapley"

: Rapid cycle analysis (RCA) is an established and efficient methodology that has been traditionally utilized by United States health authorities to monitor post-approval vaccine safety. Initially developed in the Vaccine Safety Datalink (VSD) in early 2000s, RCA has evolved into a valuable approach for timely post-approval signal detection. Due to the availability of additional near real-time data sources and enhanced analytic approaches, the use of RCA has expanded.

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Objectives: Although many people who are incarcerated have risk factors for hepatitis A virus (HAV) infection, the proportion of hepatitis A cases among people with a recent incarceration is unknown. We examined the relationship between recent incarceration and HAV infection during community-based, person-to-person outbreaks to inform public health recommendations.

Methods: The Centers for Disease Control and Prevention surveyed health departments in 33 jurisdictions reporting person-to-person HAV outbreaks during 2016-2020 on the number of outbreak-associated cases, HAV-infected people recently incarcerated, and HAV-associated hospitalizations and deaths.

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Article Synopsis
  • The study analyzed 112 deaths attributed to SARS-CoV-2 among individuals under 21 in the U.S. between February and July 2020, highlighting demographic and clinical characteristics.* -
  • Most decedents were male (63%), with a median age of 17, and a significant number identified as Black (28%) or Hispanic (46%); many had underlying health conditions like obesity and asthma.* -
  • Children who died from COVID-19 were more likely to have pre-existing health issues compared to those who met criteria for multisystem inflammatory syndrome (MIS-C), which affected 14% of the decedents.*
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We describe coronavirus disease (COVID-19) among US food manufacturing and agriculture workers and provide updated information on meat and poultry processing workers. Among 742 food and agriculture workplaces in 30 states, 8,978 workers had confirmed COVID-19; 55 workers died. Racial and ethnic minority workers could be disproportionately affected by COVID-19.

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Article Synopsis
  • Since February 2020, the U.S. has reported about 6.5 million COVID-19 cases and approximately 190,000 deaths, with a focus on individuals under 21 years old.
  • Among the 121 deaths in this age group during the early pandemic, 63% were males, and most were aged between 10-20 years, with a significant percentage being Hispanic and Black.
  • About 75% of those who died had underlying medical conditions, highlighting the need for ongoing monitoring and effective prevention strategies as schools reopen.
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