Evaluation of aural masses submitted as inflammatory polyps in 20 dogs (2000-2020).

Background: Canine non-neoplastic aural polypoid masses (APMs) are uncommon, with few published studies.

Objectives: The aim of this retrospective study was to characterise the clinical presentation, diagnostic imaging and histopathological results for APMs submitted as aural inflammatory polyps (AIPs).

Animals: Twenty dogs with APMs evaluated at a veterinary teaching hospital.

Pathology in Practice.

In collaboration with the American College of Veterinary Pathologists.

Extensive progressive pigmented viral plaques in a Chihuahua dog.

Extensive exophytic pigmented viral plaques developed on a Chihuahua dog causing pruritus and discomfort. Neither the medical treatments used nor a papillomavirus vaccine resulted in clinical improvement. Laser surgery removed some plaques, yet others developed.

Transient Horner's syndrome and ipsilateral facial hypopigmentation in an acromelanistic cat.

Horner's syndrome (HS) occurs when the sympathetic nerve pathway is disrupted. This case report describes a cat with acromelanism that developed unilateral facial hypopigmentation concurrently with HS after an oesophagostomy tube was placed. Both the hypopigmentation and HS resolved completely following removal of the oesophagostomy tube.

Preliminary study of the stability of dexamethasone when added to commercial veterinary ear cleaners over a 90 day period.

Background: Topical corticosteroids are commonly used in the management of allergic otitis externa to diminish inflammation. A common strategy is to make compounded solutions of dexamethasone in ear cleaner.

Hypothesis/objectives: The objective of this study was to determine the stability of dexamethasone when added to four commercial ear cleaners (ec): designated ecA, ecB, ecC and ecD.

A case of atypical multifocal nodular eosinophilic dermatosis in a Labrador retriever dog.

Background: A dog with gastrointestinal signs and a history of administration of multiple drugs developed acute multifocal to coalescing ulcerative nodules and a large plaque.

Objective: To describe abnormal nodular clinical lesions with an unexpected superficial and deep severe eosinophilic perivascular to interstitial inflammation.

Animal: A 7-year-old spayed female Labrador retriever METHODS AND MATERIALS: Blood tests, faecal and urinalysis, and abdominal radiographs were performed; skin biopsy samples were taken for cytological, culture and histopathological analyses.

Randomized control trial of Tools of the Mind: Marked benefits to kindergarten children and their teachers.

The kindergarten program, Tools of the Mind (Tools), has been shown to improve executive functions (as assessed by laboratory measures) and academic performance. The objective here was to see if Tools can improve executive functions in the real world (in the classroom), academic outcomes not previously investigated, reduce bullying and peer ostracism, and increase teachers' and students' joy in being in the classroom. This first randomized controlled trial of Tools in Canada included 351 kindergarten children (mean age 5.

Assessment of the clinical accuracy of serum and saliva assays for identification of adverse food reaction in dogs without clinical signs of disease.

Objective: To assess the clinical accuracy of 2 serum-based assays and 1 saliva-based assay for detection of adverse food reaction (AFR) in dogs without clinical signs of disease.

Animals: 30 healthy client-owned dogs.

Procedures: Dog owners completed an online survey to collect comprehensive information about their pets' diet history.

Case-Based Learning in Dermatology.

Importance: The instruction of dermatology can be challenging due to its large scope, heavy clinical nature, and limited curriculum space. Case-based learning (CBL) is an emerging education paradigm and has no current literature on its use in dermatology.

Objectives: Assess CBL in undergraduate dermatology medical education.

An unresponsive progressive pustular and crusting dermatitis with acantholysis in nine cats.

Background: Between 2000 and 2012, nine cats were examined with a visually distinctive, progressive crusting dermatitis that was poorly responsive to all attempted therapies.

Objectives: Documentation of clinical and histopathological findings of this disease.

Animals: Nine privately owned cats.

Afoxolaner and fluralaner treatment do not impact on cutaneous Demodex populations of healthy dogs.

Background: Fluralaner and afoxolaner are isoxazolines licensed for the treatment of flea and tick infestations. Isoxazolines have also shown efficacy for treatment of demodicosis. Nothing is known about the impact of these compounds on the populations of Demodex in healthy dogs.

Clinical characteristics of doxorubicin-associated alopecia in 28 dogs.

Background: Chemotherapy-induced alopecia (CIA) is common in humans, but there are limited reports describing the clinical features of CIA in dogs.

Objectives: To describe the epidemiological and clinical characteristics of doxorubicin-associated alopecia (DAA) in canine patients at a teaching hospital from 2012 to 2014.

Animals: Signalment, diagnosis, treatment protocols and clinical examination findings were recorded in 150 dogs treated with doxorubicin from 2012 to 2014.

Treatment of perianal fistulas with human embryonic stem cell-derived mesenchymal stem cells: a canine model of human fistulizing Crohn's disease.

Aim: To evaluate the safety and efficacy of intralesional injection of human embryonic stem cell (hESC)-derived mesenchymal stem/stromal cells (MSCs) in canine anal furunculosis dogs.

Materials & Methods: Dogs naturally develop an immune-mediated disease called canine anal furunculosis, which shares many features with human fistulizing Crohn's disease.

Results: The hESC-MSCs were well tolerated and 1 month postinjection, accompanied by reduced serum levels of IL-2 and IL-6, two inflammatory cytokines associated with Crohn's disease.

A breast reconstruction needs assessment: How does self-efficacy affect information access and preferences?

Background: Breast cancer patients requiring mastectomy do not consistently receive information about post-mastectomy breast reconstruction (PMBR) surgery from the treatment team. Patients have varying levels of self-efficacy, defined as one's confidence in their ability to gather information and make health-related decisions. The present preliminary study was designed to evaluate the relationship between self-efficacy and access to PMBR information.

Calcinosis cutis in dogs: histopathological and clinical analysis of 46 cases.

Background: Calcinosis cutis is well recognized in dogs with endogenous hyperglucocorticism and iatrogenic hyperglucocorticism, but the pathogenesis is still unclear.

Objectives: The objectives of the study were to identify possible correlations between histopathological patterns of dermal mineralization in skin biopsies and underlying causes for calcinosis cutis in dogs, as well as to determine breed predilection and age of onset for dogs within a hospital population. In addition, mineral analysis was performed on four biopsy samples.

Oral vitamin A as an adjunct treatment for canine sebaceous adenitis.

Medical records of dogs with sebaceous adenitis diagnosed by histopathology over an 18-year period were reviewed. From a total of 40 cases, 24 were treated with oral vitamin A. Dogs ranged from 9 months to 12 years of age at the time of disease onset.

Overview of flea allergy dermatitis.

Flea allergy dermatitis, or flea-bite hypersensitivity, is the most common small animal dermatologic condition. In some regions of the world, it is the most commonly seen canine disease. This disease does not exist in locations that are inhospitable to fleas, such as those at elevations above 1500 ft or with low humidity (e.