Publications by authors named "Andrea L Murray"

Article Synopsis
  • Very preterm (VP) children are at higher risk for memory and emotional issues, and this study explored the impact of VP birth on specific white matter tracts related to these functions.
  • Using advanced imaging techniques, researchers analyzed key brain structures in 144 VP children and 33 full-term children, finding that VP children exhibited changes in white matter structure, particularly in areas like the fornix and medial forebrain bundle.
  • The study suggests that altered white matter tracts are linked to poorer episodic memory outcomes in VP children, highlighting the need for further research to better understand these relationships and predict individual outcomes.
View Article and Find Full Text PDF

Our recently published M-CRIB atlas comprises 100 neonatal brain regions including 68 compatible with the widely-used Desikan-Killiany adult cortical atlas. A successor to the Desikan-Killiany atlas is the Desikan-Killiany-Tourville atlas, in which some regions with unclear boundaries were removed, and many existing boundaries were revised to conform to clearer landmarks in sulcal fundi. Our first aim here was to modify cortical M-CRIB regions to comply with the Desikan-Killiany-Tourville protocol, in order to offer: (a) compatibility with this adult cortical atlas, (b) greater labeling accuracy due to clearer landmarks, and (c) optimisation of cortical regions for integration with surface-based infant parcellation pipelines.

View Article and Find Full Text PDF

Background: Preterm birth is associated with altered brain development, with younger gestational age (GA) at birth often associated with greater brain volume reduction. Such volume alterations at term equivalent age (TEA) have been found with differing magnitude across different brain regions, although this has mostly been investigated with regards to whole tissue volumes and large-scale subdivisions. In addition to degree of prematurity, many other perinatal factors have been found to influence brain structure and development in infants born preterm.

View Article and Find Full Text PDF

Objective: This longitudinal study investigated changes in neurocognitive functioning from childhood to early adolescence in a sample of children diagnosed with DSM-IV attention-deficit hyperactivity disorder (ADHD). It also compared the neurocognitive trajectories of children who continued to meet the diagnostic criteria for ADHD at follow-up and those in partial remission.

Methods: Children diagnosed with ADHD (N = 55) were tested at baseline (M = 7.

View Article and Find Full Text PDF

Investigating neonatal brain structure and function can offer valuable insights into behaviour and cognition in healthy and clinical populations; both at term age, and longitudinally in comparison with later time points. Parcellated brain atlases for adult populations are readily available, however warping infant data to adult template space is not ideal due to morphological and tissue differences between these groups. Several parcellated neonatal atlases have been developed, although there remains strong demand for manually parcellated ground truth data with detailed cortical definition.

View Article and Find Full Text PDF

Blood products are critical to health systems and donations by voluntary nonremunerated donors are recommended. Worldwide, however, only around 5% of those eligible to donate do so and around half of those never return to donate again. This review focuses on what deters first-time donors, what predicts their retention, and what interventions may promote retention of this group.

View Article and Find Full Text PDF

While attention impairments are commonly observed in very preterm (<32weeks' gestational age) children, neuroanatomical correlates of these difficulties are unclear. We aimed to determine whether the microstructural organization of key white matter tracts thought to be involved in attention (cingulum bundle, superior longitudinal fasciculi, reticular activating system, and corpus callosum) were altered in very preterm children compared with term-born controls. We also aimed to determine whether alterations in microstructural organization of these tracts were associated with attention functioning in very preterm children.

View Article and Find Full Text PDF
Article Synopsis
  • This study looked at how well very preterm and very low birth weight kids pay attention and think quickly as they grow older.
  • They checked 198 kids born really early or small, along with 70 other kids who were born on time, to see if the condition of their brains at birth could predict how they’d do later.
  • By age 7, the early-born kids didn't do as well on attention and processing speed tests compared to their peers, and kids with more brain issues at birth tended to struggle more with these skills.
View Article and Find Full Text PDF

To our knowledge, this is the first study to investigate cognitive outcome in patients with large or surgically inaccessible cerebral arteriovenous malformations (AVMs), who were treated with hypo-fractionated stereotactic radiotherapy (HSRT). A sample of 10 patients with AVMs was assessed up to 3.5 years post-HSRT.

View Article and Find Full Text PDF
Article Synopsis
  • This study looked at what encourages people to donate blood by combining results from many other studies.
  • It found that good feelings about donating, confidence in their ability to donate, and past experience donating all help people decide to donate blood.
  • The research also showed that if someone has a bad experience while donating, they might be less likely to donate again later.
View Article and Find Full Text PDF