Outcomes associated with prehospital epinephrine in adult and pediatric patients with anaphylaxis.

Background: Prompt epinephrine administration is important to improve outcomes in anaphylaxis.

Objective: To assess the impact of prehospital epinephrine on clinical outcomes of hospital admission, biphasic reactions, and emergency department (ED) length of stay (LOS) in a cohort of ED patients who had anaphylaxis including both children and adults.

Methods: We conducted a single-center prospective and retrospective cohort study of patients who had anaphylaxis from April 2008 to December 2022.