Publications by authors named "Andrea Iovine"
Carbohydr Res
January 2025
Article Synopsis
- Capsular polysaccharide (CPS) from the bacterial pathogen Acinetobacter baumannii is a key factor in its virulence, specifically the KL58 variant produced by the strain MRSN 31468.
- The CPS structure is characterized as a branched tetrasaccharide containing various sugar units, including glucose, galactose, N-acetyl-galactosamine, and a unique acid, indicating complex biosynthesis processes.
- The study identified specific genes responsible for synthesizing components of CPS, noting that an acetyltransferase linked to a prophage may influence its structural modifications, while a related CPS variant contains a different epimer not present in MRSN 31468.
