Publications by authors named "Andrea I Boyd"
Article Synopsis
- Nasal colonization by certain bacteria increases infection risk, while others are linked to health; this study used human nasal epithelial organoids (HNOs) to explore these dynamics.
- HNOs were successfully colonized with three bacterial species for up to 48 hours, showing minimal harm and allowing for the bacteria to localize in the mucus.
- The research identified specific immune responses to the bacterial species, indicating that some bacteria trigger inflammation while others modulate immune signaling without causing infection.
Aging is a complex biological process that is characterized by low-grade inflammation, called inflammaging. Aging affects multiple organs including eye and lacrimal gland. Tumor necrosis factor (TNF) is a pleiotropic cytokine that participates in inflammation, activation of proteases such as cathepsin S, and formation of ectopic lymphoid organs.
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