Publications by authors named "Andrea Fiorillo"

Background: Eating disorders (EDs) have traditionally been studied among heterosexual cisgender women, but recent research highlights a higher prevalence in LGBTQIA+ individuals.

Aims: This study aims (1) to investigate the association between different groups based on gender identity and sexual orientation (GISO) and experiencing eating symptoms, and (2) to explore the extent to which self-perceived discrimination and adverse conditions explain this association.

Methods: We administered an online survey to assess eating symptoms using the Eating Disorder Examination Questionnaire (EDE-Q 6.

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  • This systematic review investigates the mental health and treatment access of Transgender Inmates (TGI) in correctional facilities, analyzing their specific challenges.
  • The meta-analysis of 13 studies indicates that TGI experience significantly higher risks of depression, PTSD, and suicide attempts compared to non-TGI inmates.
  • The study emphasizes the need for policy reforms and staff training to create safer and more supportive environments for TGI in prisons.
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  • * Many RAS face significant barriers in accessing mental health services, resulting in a higher likelihood of being subjected to coercive measures like involuntary hospitalization.
  • * The review, based on 23 articles, emphasizes the need for preventive strategies to reduce the use of harmful coercive interventions within the RAS population.
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To assess the longitudinal associations of genomic and exposomic liabilities for schizophrenia, both independently and jointly, with distressing psychotic experiences (PEs) and their persistence in early adolescence. The Adolescent Brain and Cognitive Development Study data from children with European ancestry were used (n=5,122). The primary outcome was past-month distressing PEs at 3-year follow-up.

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Introduction: Migrants face numerous risk factors for mental disorders, including stressors and traumatic events during the pre-, peri-, and post-migratory phases. Acculturation stress, a significant post-migratory stressor, can adversely affect mental health during the cultural adaptation process. This study aims to assess the clinical implications of acculturation stress in migrants admitted to a psychiatric intensive care unit, with a focus on identifying predictors of acculturative stress and their impact on clinical outcomes.

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Background: Health professionals from different specialties in medical and psychological areas play an important role in diagnosis and treatment of eating disorders (EDs). This study aimed to identify gaps in knowledge about the diagnosis, etiology, and management of EDs and to assess health professionals' attitudes towards these illnesses.

Methods: A new questionnaire was developed and validated.

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: Radicalization, a complex and multifaceted phenomenon, has been a subject of increasing concern in recent years, particularly due to its potential connection to acts of mass violence and terrorism. This systematic review examines the intricate link between radicalization and psychotic disorders, utilizing various sources such as observational studies, case reports, and series. It aims to highlight the prevalence of schizophrenia spectrum and other psychotic disorders among radicalized individuals and to define the role of mental health professionals in dealing with this issue, contributing to the development of prevention and treatment strategies.

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Introduction And Aims: Treatment-resistant depression (TRD) occurs when at least two different antidepressants, taken at the right dosage, for adequate period of time and with continuity, fail to give positive clinical effects. Esketamine, the S-enantiomer of ketamine, was recently approved for TRD treatment from U.S.

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Major depressive disorder (MDD) is a heterogeneous syndrome, associated with different levels of severity and impairment on the personal functioning for each patient. Classification systems in psychiatry, including ICD-11 and DSM-5, are used by clinicians in order to simplify the complexity of clinical manifestations. In particular, the DSM-5 introduced specifiers, subtypes, severity ratings, and cross-cutting symptom assessments allowing clinicians to better describe the specific clinical features of each patient.

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Background: Up to 34% of patients with schizophrenia are resistant to several treatment trials. Lack of continuous and adequate treatment is associated with relapse, rehospitalization, a lower effect of antipsychotic therapy, and higher risk of side effects. Long-acting injectables antipsychotics (LAI APs) enhance compliance and improve clinical outcomes and quality of life in patients with schizophrenia, and thus it may be advisable to administer two LAI APs at the same time in cases of treatment-resistant schizophrenia.

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  • Climate change is a big problem that can harm our mental health, and Europe needs to create a shared paper discussing how they’re connected.
  • The European Psychiatric Association (EPA) is suggesting ways to make mental health care, research, and education better for the environment, like working together and using resources wisely.
  • The EPA wants everyone to know that climate change is a serious threat to mental health care and that their paper can help lots of people understand this issue better.
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  • A systematic review analyzed 64 studies (out of 5547) on burnout among medical students, using validated tools like the Maslach Burnout Inventory, and found burnout prevalence ranging from 5.6% to 88%, influenced by factors such as gender, academic stage, and life events.
  • The findings underscore the urgent need for preventive interventions to enhance coping strategies and resilience among medical students, given the significant variability in burnout prevalence.
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Background: Lithium stands as the gold standard in treating bipolar disorders (BD). Despite numerous clinical factors being associated with a favorable response to lithium, comprehensive studies examining the collective influence of clinical variables alongside psychopathological dimensions are lacking. Our study aims to enhance comprehension of lithium response in individuals with BD by integrating clinical variables with psychopathological traits and early adverse events.

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Background: Schizophrenia is a severe mental disorder characterized by positive, negative, affective, and cognitive symptoms. Affective symptoms in patients with schizophrenia have traditionally been overlooked or even neglected because they are not considered as fundamental as positive and negative symptoms in the choice of medication.

Methods: This paper aims to systematically evaluate the efficacy and safety of lurasidone in the treatment of depressive symptoms of schizophrenia.

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  • A study looked at how doctors in Europe treat people with post-traumatic stress disorder (PTSD) because there are more traumatic events happening recently.
  • Out of 611 doctors, most recommended using antidepressants like sertraline, but there were differences in medicine choices based on where the doctors were from in Europe.
  • The findings show that while many doctors agree on treatment methods, differences in practice suggest that more communication and education are needed to follow treatment guidelines better across Europe.
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The aim of this study was to prospectively assess the development and trajectories of anxiety and depressive symptoms among subjects with different mental disorders, during the 3rd wave of the COVID-19 pandemic (T0, March-April 2021) while strict containment measures were applied in Italy, and after 3 months (T1, June-July 2021), with reduced restrictive measures. A sample of 527 subjects, with different DSM-5 diagnoses, was enrolled at nine Italian psychiatric outpatient services. Assessments at T0 and T1 included the Generalized Anxiety Disorder 7-Item (GAD-7) for anxiety symptoms, and the Patient Health Questionnaire-9 (PHQ-9) for depressive symptoms.

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Background: A better characterization of educational processes during psychiatry training is needed, both to foster personal resilience and occupational proficiency.

Methods: An adequate coverage of medical residents at the national level was reached (41.86% of the total reference population, 29 out of 36 training centers-80.

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  • * The study analyzed data from the LIFESTYLE trial, focusing on adherence levels, socio-demographic differences, and the impact of a psychosocial intervention that encourages healthy lifestyle practices, including physical activity.
  • * Results showed that less than 40% of patients adhered to their treatments initially, but post-intervention, adherence improved significantly, particularly among those engaging in moderate physical activity, suggesting the intervention's effectiveness in enhancing treatment compliance.
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Background: According to the United Nations Commissioner for Refugees (UNHCR), children and adolescents represent 41% of all forcibly displaced individuals. They have to deal with conflicts, violence, and the many difficulties of flight and resettlement during a critical stage of their emotional, social, cognitive, and physical development. They are more likely to experience mental health problems during migration.

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Background: Bipolar disorder is one of the most burdensome severe mental disorders, characterized by high levels of personal and social disability. Patients often need an integrated pharmacological and non-pharmacological approach. Lithium is one of the most effective treatments available not only in psychiatry, but in the whole medicine, and its clinical efficacy is superior to that of other mood stabilizers.

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Introduction And Aims: Bipolar disorder (BD) is a severe and recurring mental illness associated with a significant personal and social burden. It has been recently hypothesized that increased levels of pro-inflammatory cytokines and cortisol, which is also associated with a reduced expression of the brain-derived neurotrophic factor (BDNF), may influence affective recurrences in BD. Our study aims to: 1) assess changes in the levels of peripheral cytokines, BDNF and salivary cortisol during acute and euthymic phases of bipolar disorder, compared to that of a sample oh healthy controls; 2) evaluate whether these changes represent a biosignature for the different phases of the illness.

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